ID A0A3B3BAR6_ORYME Unreviewed; 804 AA.
AC A0A3B3BAR6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25-like {ECO:0000313|Ensembl:ENSOMEP00000002610.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000002610.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000002610.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3BAR6; -.
DR STRING; 30732.ENSOMEP00000002610; -.
DR PaxDb; 30732-ENSOMEP00000002610; -.
DR Ensembl; ENSOMET00000012201.1; ENSOMEP00000002610.1; ENSOMEG00000003563.1.
DR GeneTree; ENSGT00940000164538; -.
DR OMA; QTCDSMS; -.
DR OrthoDB; 5475497at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd16040; SPRY_PRY_SNTX; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF12; E3 UBIQUITIN_ISG15 LIGASE TRIM25 ISOFORM X1; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 13..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 159..199
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 598..794
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 398..493
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 201..299
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 400..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..463
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..492
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 88968 MW; A4DA434E194471D9 CRC64;
MSAKLWTEEQ FNCPVCLDLP NDPVTIPCGH SYCMACIRDF WTKDDPKGIY SCPQCRQTFC
PKPPLSRNTM LAEAVEQLRK GALSSTVRDS IRSVRGGGVS SKPRLSTAAV LCDMCKKERR
AAVRSCLACM SSFCEDHLKP HQTKKSLKKH ELIAPVSNLA EKICTQHKYM QEFFCRHCKM
FVCWLCTSNQ HKDHECVSTK IQRLEKQKVL SEIQADNQQR LKDREQELKE LKKVMEVAKN
SANRVHSETE AVVRELQESM ERLQELLEEA LDQTGLEKMG QAQEVVENLE GEIRERKKRD
TEMKDLSGCD DHIYYLQTCD SMSTPLEVGD FPVVLVNAEA SYEPVRSAIL ALRERVEDLC
NQELGKIIKQ VNETTLFTLK ESNRNRGAKT GILKLFSGLG PRNANSSRSA APTPSISVGV
RSDRTGLGLR VPDVRSRDTR DRANPSSPRA GNRRRRDERE TATETNLQPS PTPSRRESQS
LWSRSSQSPV IPAATPAPVL VTPAVTPAPA PAPASAPAGS GAFSRMASIS SLFRSHRRGT
TPATPVQDPP PSAANPWGMA ALSETPTEIN PSLFLDTPMP DAMIQAPAFP ALREINLDSI
QAPEPRSREE FLQYAVNLML DPNTAHKRLV LSEGNTKATL QGASQPYPDS PQRFDGWTQV
MCQAPLQAQR CYWEVDWRGR GSSMGVAYSS LSRKGSDARS GIGYNAQSWT LELSDTCCSA
MHDNQKKDIP VTYSPRLGIY LDMISGTLGF YSVADSMVPL HTFRANFTQP VYAVFGVGSG
VGVGLDFALG QFSSSSDSIK ICPL
//
