ID A0A3B3BBX9_ORYME Unreviewed; 843 AA.
AC A0A3B3BBX9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Dipeptidyl aminopeptidase-like protein 6 {ECO:0000256|ARBA:ARBA00040948};
DE AltName: Full=Dipeptidyl peptidase 6 {ECO:0000256|ARBA:ARBA00042016};
DE AltName: Full=Dipeptidyl peptidase VI {ECO:0000256|ARBA:ARBA00041991};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000002707.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000002707.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3BBX9; -.
DR STRING; 30732.ENSOMEP00000002707; -.
DR PaxDb; 30732-ENSOMEP00000002707; -.
DR Ensembl; ENSOMET00000012041.1; ENSOMEP00000002707.1; ENSOMEG00000003729.1.
DR GeneTree; ENSGT00940000156280; -.
DR OrthoDB; 2876738at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 2.140.10.30; Dipeptidylpeptidase IV, N-terminal domain; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR InterPro; IPR002469; Peptidase_S9B_N.
DR PANTHER; PTHR11731:SF20; DIPEPTIDYL AMINOPEPTIDASE-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR11731; PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED; 1.
DR Pfam; PF00930; DPPIV_N; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 79..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 178..542
FT /note="Dipeptidylpeptidase IV N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00930"
FT DOMAIN 624..825
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 33..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 95694 MW; D0B2DB48079BC9F5 CRC64;
MASLYQRFTG KINTNNSFPH PPEASHLLGG QALDEENGAK PPHPLTDGRA HGQTRKKCLR
EDEDDLVGSA PPQRNWKGIA IALLVILIIC SLIVTSVILL TPSEDDSLAL KKKITIEDVF
GPDLHIHDPD AKWLSENELM FRSRNGNVIR LNVETKETRT VVPKQLFDRA KATKYQVSPD
MQHVLFAFDV KPIYQHSYVA KYIIYSLVKQ DSWPLNPPEV QEAVLQFAGW GPQGQQLIFI
FENNIYYRAT VESRSIRLVS TGKEGVVFNG LADWLYEEEI LQTHVAHWWS PDGLRLAYMT
INDTLVPKME VPFFTGSAYP ASLDYHYPKA GKENPAVHLS VVNLHGPLHT VGMKKPDDPR
IGREYYITMV KWATNTKLAV NWLNRAQNNS ILTLCEATTG VCVKKHEDES ESWLHRQNEQ
PLFSKDGHKF FFTRAIPQGG RGKFFHISMS TSLPNSSTDI LQSLTSGDWD VTRILAYNHQ
KNLIYFLSTE DDPKRRHLYS ADTIPPFNRC CLSCEFKCGY VDVSFSHDMQ FFLLNCKGPD
IPSVAVYRTE DKQKMYDVET NQQVNITYNN LQTPRVENKT INIDDYTLTM QILKPAGFIN
TASYPLLLLV DGTPGGQMVT EQFQVDWATV LVSSFSTIVI RFDGHGSGFQ GTNLLHKVRR
KLGKLEERDQ LEALRVISKE PYIDKSRMGV YGKAYGGYLA TMLLSSEEFT QLKCGAAVSP
ITDFELYASA FSERYLGPKT DSRVYAMTNL ANRAGQLLEK QFLIIHPTAD EKVHFQHTAK
FINHLISEKA NYTLQIYPDE GHFLHSEGAR QHLSQSLVNF FEECFRVPDM PTDDQQEENE
GDS
//
