ID A0A3B3BEG9_ORYME Unreviewed; 844 AA.
AC A0A3B3BEG9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Solute carrier family 4 member 11 {ECO:0000313|Ensembl:ENSOMEP00000003870.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000003870.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000003870.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993}.
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DR AlphaFoldDB; A0A3B3BEG9; -.
DR Ensembl; ENSOMET00000010097.1; ENSOMEP00000003870.1; ENSOMEG00000004833.1.
DR GeneTree; ENSGT00940000154894; -.
DR OMA; AIFHWIV; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF82; SOLUTE CARRIER FAMILY 4 MEMBER 11; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 338..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..408
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..547
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 567..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..676
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 713..732
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 738..756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..805
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 811..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 306..789
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 30..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 844 AA; 95314 MW; 65710594C0E4407F CRC64;
METNKVLHFV PSEAPPSGMS KNGYFFQEME QREAEQDEVS EGREETQDSP IACGDDIHLY
DNQISPGTDA DDCGCVLLNT SRRYVKLMNF EEEVRALRDL DGFLAKASIL LDETAASLDD
VLKRMLHHVG QDSNAYEPSC NFEEVMSMLF TDAGAQEVNV HLLSETIQGV TATATGVQYQ
QSWLCILCNV KHLQRRHVCI SRLERPQNWG ENCCEVRYVI LILAPSKMKS TKTAMELGRT
FATLFSDISF RQKLLETKTQ EEFKEALLFQ RHQLTAANQQ PTALGKEETD PRSHKPLKCK
DFFKVGRGIY EDLCRRLPFY PSDFTDGIVG SNKTLLKYMT TAIFLYIAIL LPAIAFGSLN
DESTRGEIDV RKTIIGQSIG GIIYSLCAGS PLVIPLTTAP LAIFISVIRG ICDDYNLDFP
AFYACIGLWN CLFLILGGIF NVSLLMKLFK RSTEEVIALF ISIAFVVDAV KGTVKIFQRY
YNAPTSANRS LEDFRQGGEV LEGNRSEVAA RLVLNALPES IIQCSRERPV LCLLLMLGTL
WMGYTLYQFK RSPFLHAKVR EVLSDCALPI SVLLFSFIGS YIFSDIELPV FKVHDRPIFN
VAPFERLSAM NVVSAMGLGF LLALLIFIDQ NIVVSLTNAP ENRLLKGTAY HWDLMLSGLI
NILMSVLGLP WMHAAFPHST LHVRQLAFVE QRVEGGHLYE TIVQVKETRL TSLAANIFIG
VSLLLLPVPL QWIPKPVLYG LFLYIALTSI DGNQMCDRMA LLLKEQTSYP PTHYIRKVPQ
RKIHYFTFLQ MMQLLVLCTF GMYPIPYMKM IFPLVMILLI PIRNSVLPHI IEAKYLDIMD
AQHM
//
