ID   A0A3B3BF39_ORYME        Unreviewed;       481 AA.
AC   A0A3B3BF39;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Paired box protein Pax-2a {ECO:0000313|Ensembl:ENSOMEP00000003817.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000003817.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000003817.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3B3BF39; -.
DR   STRING; 30732.ENSOMEP00000003817; -.
DR   PaxDb; 30732-ENSOMEP00000003817; -.
DR   Ensembl; ENSOMET00000010198.1; ENSOMEP00000003817.1; ENSOMEG00000004755.1.
DR   GeneTree; ENSGT00940000157412; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0034672; P:anterior/posterior pattern specification involved in pronephros development; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0021588; P:cerebellum formation; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0061386; P:closure of optic fissure; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0021703; P:locus ceruleus development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0030917; P:midbrain-hindbrain boundary development; IEA:Ensembl.
DR   GO; GO:0043049; P:otic placode formation; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0035775; P:pronephric glomerulus morphogenesis; IEA:Ensembl.
DR   GO; GO:0072114; P:pronephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0060118; P:vestibular receptor cell development; IEA:Ensembl.
DR   CDD; cd00131; PAX; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR   InterPro; IPR001523; Paired_dom.
DR   InterPro; IPR022130; Pax2_C.
DR   InterPro; IPR043565; PAX_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45636:SF45; PAIRED BOX PROTEIN PAX-2A; 1.
DR   PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR   Pfam; PF00292; PAX; 1.
DR   Pfam; PF12403; Pax2_C; 1.
DR   PRINTS; PR00027; PAIREDBOX.
DR   SMART; SM00351; PAX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00034; PAIRED_1; 1.
DR   PROSITE; PS51057; PAIRED_2; 1.
PE   4: Predicted;
KW   Paired box {ECO:0000256|ARBA:ARBA00022724};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          19..152
FT                   /note="Paired"
FT                   /evidence="ECO:0000259|PROSITE:PS51057"
FT   REGION          156..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          223..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          327..348
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   481 AA;  51643 MW;  B37064818D62045B CRC64;
     MDIHCKADPF SAMHLSHAGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ
     LRVSHGCVSK ILGSYQKAFQ RYYETGSIKP GVIGGSKPKV ATPKVVDKIA EYKRQNPTMF
     AWEIRDRLLA EGVCDNDTVP SVSSINRIIR TKVQQQFHPS PDGSVTPLST PGHTIVPSTA
     SPPVTSASND PVGSYSINGI LGIPRSNGEK RKRDDVLWSG NHLDGRKIGH YGSDGSGPGS
     DSQGSVESLR KHLRADAFTQ QQLEALDRVF ERPSYPDVFP TSEHIKPEQA NEYSLPSLNA
     GLEDVKPSLS TSASSDLASS VSQSYSVVTD SHPSYPPSMS VKREPHEASF APFTPSSALA
     DVLPHQPSLS VDASTPSFLS HAHGSCYSQP FIAGRDMAST TLPGYPPHVP PTGQGSYPTS
     TLAGMVPGGD FSGNPYSHPQ YTTYNEAWRF SNPALLSSPY YYSAASRGSA PPAAATAYDR
     H
//