ID A0A3B3BH14_ORYME Unreviewed; 427 AA.
AC A0A3B3BH14;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=26S protease regulatory subunit 6A {ECO:0000313|EMBL:KAF6731132.1};
DE SubName: Full=Proteasome 26S subunit, ATPase 3 {ECO:0000313|Ensembl:ENSOMEP00000004474.1};
GN ORFNames=FQA47_006754 {ECO:0000313|EMBL:KAF6731132.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000004474.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000004474.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|EMBL:KAF6731132.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bigg-433 {ECO:0000313|EMBL:KAF6731132.1};
RX PubMed=32938378;
RA Liang P., Saqib H.S.A., Ni X., Shen Y.;
RT "Long-read sequencing and de novo genome assembly of marine medaka (Oryzias
RT melastigma).";
RL BMC Genomics 21:0-0(0).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; WKFB01000218; KAF6731132.1; -; Genomic_DNA.
DR STRING; 30732.ENSOMEP00000004474; -.
DR PaxDb; 30732-ENSOMEP00000004474; -.
DR Ensembl; ENSOMET00000009103.1; ENSOMEP00000004474.1; ENSOMEG00000005432.1.
DR GeneTree; ENSGT01020000230346; -.
DR OMA; NKISHEH; -.
DR OrthoDB; 1707207at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR Proteomes; UP000646548; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF7; 26S PROTEASOME REGULATORY SUBUNIT 6A; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Hydrolase {ECO:0000313|EMBL:KAF6731132.1};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Protease {ECO:0000313|EMBL:KAF6731132.1};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000646548}.
FT DOMAIN 207..346
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 427 AA; 47814 MW; 9EE6D85910F66A70 CRC64;
MASLSDKSVW DEVEDGIGEE VLKMSTEEIV QRTRLLDSEI KIMKSEVLRV THELQAMKDK
IKENTEKIKV NKTLPYLVSN VIELLDVDPN DQEEDGANVD LDSQRKGKCA VIKTSTRQTY
FLPVIGLVDA EKLKPGDLVG VNKDSYLILE TLPTEYDSRV KAMEVDERPT EQYSDIGGLD
KQIQELVEAI VLPMNHKEKF ENLGIQPPKG VLMYGPPGTG KTLLARACAA QTKATFLKLA
GPQLVQMFIG DGAKLVRDAF ALAKEKAPSI IFIDELDAIG TKRFDSEKAG DREVQRTMLE
LLNQLDGFQP NMQVKVIAAT NRVDILDPAL LRSGRLDRKI EFPMPNEEAR ARIMQIHSRK
MNVSLDVNYE ELARCTDDFN GAQCKAVCVE AGMIALRRGA TELNHEDYME GILEVQAKKK
ANLQYYA
//
