ID A0A3B3BHK9_ORYME Unreviewed; 699 AA.
AC A0A3B3BHK9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA-binding protein RFX2 {ECO:0000256|ARBA:ARBA00039910};
DE AltName: Full=Regulatory factor X 2 {ECO:0000256|ARBA:ARBA00042136};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000004702.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000004702.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B3BHK9; -.
DR Ensembl; ENSOMET00000008709.1; ENSOMEP00000004702.1; ENSOMEG00000005761.1.
DR GeneTree; ENSGT01050000244879; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR007668; RFX1_trans_act.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619:SF17; DNA-BINDING PROTEIN RFX2; 1.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR Pfam; PF04589; RFX1_trans_act; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 184..259
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 661..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..699
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 77577 MW; FE0F107ABDF7B84B CRC64;
MQNAEGGSDT TTTVAALRTS SSAQAPVVQP VPASQQRVLV QAVGSAQKGG QVQQISVPRV
QQVPQQVQQV QHVYPSQVQY VGESGEAVYT NGTIRAAYSY NPESQLYGQN SGGTYFDSQA
GGAHVTTVVS SASGGVPPHG MVGIAMEVGS SHIISSGSPY LIHGGSMEGS RNHISHSSRS
SSAMLQWLLD NYETAEGVSL PRCSLYNHYL RHCQEQKLDP VNAASFGKLI RSVFMGLRTR
RLGTRGNSKY HYYGIRVKPD SPLNRLQEDT QYMAMRQQPV HQKQRFKPLQ KVDSMSDSLC
GGPQACNSTP EQSVAAQSQH HQHYIDTSHT LPQFPPLDVG SQPLPERINM SDIKKLKTLY
RDHCEATLDV VMNLQFHYIE KLWQTFWCST APSSDGSTSI PSSDDDMEGT IPREKLVALC
KYEPVRLWMR SCDHILYQAL VEVLIPDVLR PVPSTLTQAI RNFAKSLEGW LTNAMTSFPQ
EIVRTKVAVV SAFAQTLRRY TSLNHLAQAA RAVLQNTSQI NQMLSDLNRV DFANVQEQAS
WVCQCDESVV QRLEQDFKVT LQQQSSLDQW ATWLDNVVSQ VLKPHQGNPS FPKAARQFLL
KWSFYSSMVI RDLTLRSAAS FGSFHLIRLL YDEYMFYLVE HRVAQATGET PIAVMGEVNA
SDEMSSMGGG GGDDDASRET SEPSVKRERI DMSQSLQEM
//
