ID A0A3B3BKZ3_ORYME Unreviewed; 1571 AA.
AC A0A3B3BKZ3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Roundabout homolog 1-like {ECO:0000313|Ensembl:ENSOMEP00000005777.1};
GN Name=ROBO1 {ECO:0000313|Ensembl:ENSOMEP00000005777.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000005777.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000005777.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 30732.ENSOMEP00000005777; -.
DR PaxDb; 30732-ENSOMEP00000005777; -.
DR Ensembl; ENSOMET00000006920.1; ENSOMEP00000005777.1; ENSOMEG00000006795.1.
DR GeneTree; ENSGT00940000154477; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR CDD; cd07693; IgC_1_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR PANTHER; PTHR44170:SF49; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1571
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017442592"
FT DOMAIN 70..166
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 172..259
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 264..348
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 353..448
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 457..545
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 564..658
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 677..775
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 780..876
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 20..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1115..1134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1231..1259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1272..1307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1387..1437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1449..1555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1116..1130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1231..1250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1396..1413
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1476..1503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1571 AA; 171522 MW; D0350B01C944AAC9 CRC64;
MLALHVVVVI SLLSASETEQ SRSVIVSSDA EKHRGSQEVS TKSPESKTEP DQDGNLGYKG
SRLRQEDFPP RIVEHPSDLI VSKGEPATLN CKAEGRPPPT VEWYKDGERV ETDRDNPRSH
RMLLPSGSLF FLRIIHGRRS KPDDGSYVCV ARNYLGQAIS HNASLEVAIL RDDFRQNPVD
VMVAVGEPAV LECQPPRGHP EPTISWRKDG ANLDDRDERI TIRSGKLMIT NTLKTDAGKY
ICVATNMLGE RESETAELTV LERPTFVKRP SSVVVLTDES VEFHCVVQGD PVPIVRWRKD
DSDLPKGRYE VVEDHTLIIR QVTSSDEGSY TCVVENMVGK SEASASLTVH VPPAFAMHPR
NQVVSVGRTV TFQCEATGNP QPAIFWQREG SESLLFSYQP PQPFSRLSVS QMGSLTITDV
QRSDAGFYSC QALNIAGSVI TKALLEVSDA GSDYPPPFIK QGPSNQTVLV DSTVELGCQT
VGSPPPTVHW RKDGVILSLA DSRMSVTETG SLKIYHTELG DSGLYTCSAS NPGGEASWTA
FLQVQEFGVV KSVHPVEKNM MPPAPSKPEV TNVSQTSVTL SWKSSPNNDK LPTSYLIEAF
SYTLGNRWVT LAEHVRAETL VLRNLKPGAV YLFMIRAVNA YGLSDPSPIS ESVRTQDSTA
TIKGVDHRHI QSELGDVVIH LHMPTILSGS AVRLQWMVEQ QSPYIQGFKV LYRLSAEHGQ
PEVQWSVLEV HGSQEDSVVI SHLKKGSIYE FKVRPFFDEF QGADSEVKVV RTLDEVPRRA
PQGVTVTKSD ANGTAILVSW KPPPEAGEDG FIQEYKIWCL GNESRYHVNQ SVDGSTFAVL
ISSLAPGIRY SVEVAASNGA GLGVKSEAAF FQFDSAGQMM VISDKRDALS HISDVVKQPA
FIAGIGATCW FVLMIFSVWL YRHRKKRSGL SSTYTGIRKV PSFTFTPTVA YQRGESACSA
GRPGPLSMGE PLNQLWLPDN WPNPSANHLD CGINCCNNGN GTSDSNMTTY SRPADCIANY
GNHPDNKQGG QLGTAIYSDI NLSNKLSEIK TINNLGYVSP GGDSTGTYEP IPYATTQLIQ
ASIKNKGATL SEPLDIPCWK QPPNLPPITK EMAAQMQHSM AEQSSKDLQG SEGGVIHPKL
MLNHTHNHGT GSSSHSSDRG SSSTSGSAIQ RKGVRAPKTS KHNGVSWGEQ LSSVQADAWD
CDEYSLPMEG SFDPEEKTAD APSLLVRAST PTEGTCCQTP ASSSQGGLSN GLHDGDEHFT
HTYSSIPLCV DTDGQEESEE EAREEENPGE NPYSQPYNHQ KHKHQLHPLS SHKLLLHGRE
QTPTSSTGDL DRSVTGSMVN SWGSASEDNI SSGRSSVVST SEGSFFTDGD FNQTAASSRD
IVGVRVNRYS EESGRRQQRA SSPMSTDSNM SPAITHKRPR RHKHNHSGQQ DCKPTDVFSD
DTCMPLTFTN QMCHGDNKVR GATLPRMGSG ESRGRRGSAG THRVKEGSSE QSKGQDKHKI
SSAVKGNNKN RQHSEFGDVP LYSRPSFPPG HRELGSNALS FQSCGNSRTK HAELEGPAVQ
VEEFLKSQEA L
//
