ID   A0A3B3BLG5_ORYME        Unreviewed;       661 AA.
AC   A0A3B3BLG5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Forkhead box O3 {ECO:0000313|Ensembl:ENSOMEP00000006411.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000006411.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000006411.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PROSITE-
CC       ProRule:PRU00089}.
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DR   AlphaFoldDB; A0A3B3BLG5; -.
DR   STRING; 30732.ENSOMEP00000006411; -.
DR   PaxDb; 30732-ENSOMEP00000006411; -.
DR   Ensembl; ENSOMET00000005850.1; ENSOMEP00000006411.1; ENSOMEG00000007462.1.
DR   GeneTree; ENSGT00940000161401; -.
DR   OMA; SKPNGIA; -.
DR   OrthoDB; 5385885at2759; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd20060; FH_FOXO1; 1.
DR   Gene3D; 6.10.250.1690; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR047408; FH_FOXO1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR032067; FOXO-TAD.
DR   InterPro; IPR032068; FOXO_KIX-bd.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45767; FORKHEAD BOX PROTEIN O; 1.
DR   PANTHER; PTHR45767:SF4; FORKHEAD BOX PROTEIN O3; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   Pfam; PF16676; FOXO-TAD; 1.
DR   Pfam; PF16675; FOXO_KIX_bdg; 1.
DR   PRINTS; PR00053; FORKHEAD.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT   DOMAIN          130..224
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        130..224
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          1..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..299
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          404..424
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        94..108
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..299
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   661 AA;  69604 MW;  CAF54E68798FDF02 CRC64;
     MAEAPLPDAL PDLDVAIDPD FEPQKRPRSC TWPLPRPDSG AVKPESNDII PEEEDDEEDA
     TTPSARVNGC VAAAEDQSSN SPVGDGALAS PGQESGGSPL SSHSPAAALT PSGLAAAQTP
     RKTSSRRNAW GNLSYADLIT QAIESSPEKR LTLSQIYDWM VRSIPYFKDK GDSNSSAGWK
     NSIRHNLSLH SRFIRVQNEG TGKSSWWMIN PEGGKGGKAP RRRAVSMDNS NKYTKSARGR
     AAKKKAALQA AAAAAGEGGG DSPSGLSRWP GSPTSHSTED LDSGWTDFRS RTNSNASTVS
     GRLSPILANT ELGEVLDDEA PLSPMIYSSP GRALSPGNAM SNGKAAPAEL PRLADLTGTM
     NLNDGITDEL MDDLLDNIKL VPPSTSQNLQ NGFTFGSKPN GISLPSSTSC PSSNSSSNGG
     NNGFSNSIFG SQAIGSLRSS PMQTIQENKQ TSFTSISMSG FGTKTLQDLL NSGSHNHSDV
     MMTQSDPLMS QASSAAVNSQ NSRRGLILRN DPVMTFGTGG GIQGSQRDVL QTNNQNQSSV
     RSINGGLNLA NEANTLANAK QQLLLSPLGG NGSSTMQIDP SIFLNGTISS SSGGGVSQDR
     FPTDLDLDIF NGSLECDMDS IIRNDLMDAD GLDFNFDSLM NMNGVSNFTS TKQSSQSWVP
     G
//