ID   A0A3B3BMF0_ORYME        Unreviewed;       787 AA.
AC   A0A3B3BMF0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Tripartite motif-containing protein 46-like {ECO:0000313|Ensembl:ENSOMEP00000006292.1};
GN   Name=TRIM46 {ECO:0000313|Ensembl:ENSOMEP00000006292.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000006292.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000006292.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3BMF0; -.
DR   STRING; 30732.ENSOMEP00000006292; -.
DR   PaxDb; 30732-ENSOMEP00000006292; -.
DR   Ensembl; ENSOMET00000006047.1; ENSOMEP00000006292.1; ENSOMEG00000000180.1.
DR   GeneTree; ENSGT00940000158021; -.
DR   OrthoDB; 5383069at2759; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00063; FN3; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 4.10.830.40; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR017903; COS_domain.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR018957; Znf_C3HC4_RING-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR   PANTHER; PTHR24099:SF20; TRIPARTITE MOTIF-CONTAINING PROTEIN 46; 1.
DR   Pfam; PF00643; zf-B_box; 1.
DR   Pfam; PF00097; zf-C3HC4; 1.
DR   SMART; SM00336; BBOX; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS51262; COS; 1.
DR   PROSITE; PS50853; FN3; 1.
DR   PROSITE; PS50119; ZF_BBOX; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00024}.
FT   DOMAIN          222..264
FT                   /note="B box-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50119"
FT   DOMAIN          371..428
FT                   /note="COS"
FT                   /evidence="ECO:0000259|PROSITE:PS51262"
FT   DOMAIN          430..538
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          66..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          678..704
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          286..313
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        678..703
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   787 AA;  87508 MW;  CC8BB98D2E140BB4 CRC64;
     MAEEDLQTFT SVMDALVRIS SNMKSMEKEL LCPVCDEIVK QPVLLPCQHS VCLLCAAEVL
     VQRGYPPPDL PPEPRSPAST PSNRSPRQTH RPTPRTPDRL ERVLRTVCST YPGRRRKDTT
     LPPMIFPCPS CQQEVELGQR GLSDCFRNLT LERIVERYRH TISLGSMAIM CAFCKPPQSL
     EATKGCADCK SNFCNECFKL YHPWGTPRAQ HEHILPTNNF RPKVLTCTEH EQERLQWYCR
     SCQRLLCPVC KLRRVHHGHK VLPIAQAYQA LKDKMAKEVN FILTNQETIQ SQITQLEAAI
     KQMEANSAVA LQQLTHCIRE LGATVAERQG TLTLALEASR SRREEALFGQ AFEKQGLLEE
     AGLMAYTQEL LKETDPPSFV QAARVTHNRL VKAIENLQCF SLAADTSFRH FHLDASKEVK
     LIDSLQFIQA PLAPVIDTQK TLAYDQLFLC WRLPQDSASA WHFSVEFQRR AGGAGAVWGG
     TGSPSSSTPW QRLNEVKGTS AVIDRLQMDS VYVLRVRGCN KAGFGEYSEE VYLHTPPAPV
     LSFSLDSHWG LHADRLALGK GQTYARSVPG LSLLQAADRA LTSCHLTSDL LVADLAVTQG
     RHYWACSVEP GSYLVKVGVG QEAKLQEWFH LPQDMTSPRC DADSGHDSGA EDGQDSPPFC
     FLTVGMGKIL LPQGHAHTQS QCDSQSHGGL YSHSSSHSNL PHSHTAPLPP RLGVCLDCDK
     GRVTFYDAHS LRVLWEGHLD CSVPVCPAFC FIGGGALQLQ DLVANRSVEE PPPRRVTIQT
     RATNRSK
//