ID   A0A3B3BN22_ORYME        Unreviewed;      1744 AA.
AC   A0A3B3BN22;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Thrombospondin, type I, domain containing 7Aa {ECO:0000313|Ensembl:ENSOMEP00000006689.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000006689.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000006689.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   Ensembl; ENSOMET00000005390.1; ENSOMEP00000006689.1; ENSOMEG00000007773.1.
DR   GeneTree; ENSGT00940000155427; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 10.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   InterPro; IPR044004; TSP1_spondin_dom.
DR   PANTHER; PTHR11311; SPONDIN; 1.
DR   PANTHER; PTHR11311:SF32; TSP1_SPONDIN DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF19030; TSP1_ADAMTS; 1.
DR   Pfam; PF19028; TSP1_spondin; 6.
DR   Pfam; PF00090; TSP_1; 3.
DR   SMART; SM00209; TSP1; 13.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 10.
DR   PROSITE; PS50092; TSP1; 13.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..34
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           35..1744
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017340648"
FT   TRANSMEM        1693..1716
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          185..236
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   DOMAIN          449..504
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   DOMAIN          718..777
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   DOMAIN          857..915
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   DOMAIN          1122..1164
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   DOMAIN          1372..1425
FT                   /note="Spondin-like TSP1"
FT                   /evidence="ECO:0000259|Pfam:PF19028"
FT   REGION          254..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..506
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        263..290
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..332
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        364..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1744 AA;  194731 MW;  D0A3FED85DC405C8 CRC64;
     MGLPGGAAVS RGGLTKAPAL LLWRLGLLCF SVWALDAENA EETKPLYIWK TGPWGRCMGS
     ECGPGGSQSR AVWCSHPDGW TTLHTNCDQA ERPDNQQGCF RVCDWHKDLY GWQLGAWNQC
     VPVVMRNGGG QRPAVCSRGE EGIQTREVGC VQKADGEPAE DAICEYFEPR PRQEQACLIP
     CPRDCVVSEF TPWTLCSKTC GMGLRNRVRN VLAPPLFGGS ACPNLTEFET CQVGPCEGEE
     SLYSLRVGPW GPCSVPNSRQ VRQTDKALKE SKKRSKEADR LSKEGKNQPR ENKQVVGVNK
     QMRDDEKLYK EVEKTPREGE KPPRDGKKAS APNRKRIRAN KKADRQADRP RRQKKMKNKD
     KREKKRKEVK ERLRERGKVK DPETRELVKK RRNKNRQNRP GGKFWDLQVG YQTREVSCQH
     KSGNMEALSM CSKEVLPVTF QACVVPRDCD VTEWSEWSAC SKECYDPNNP SGGQRTRTRR
     VSQFPLSGGG ECPELEESEP CSPQADTAPP CTLNTWKTTE WTECRVDTLL SQQDRRRGNQ
     TGLCGGGIQT REVYCVQVNT ETPPNLRTKE ALRPVDSELC QGITPNTTQL CHINCPVECE
     VSPWSAWGPC TFENCQDQAT KKGFKLRKRR IINEPTGGMG NCPHLVEAIP CDDPSCFEWL
     VVKLEGCVPD NDRECGPGTQ IPQVQCVNSE GLFVEKQLCR DAILPMPTLC EVPCPKDCAL
     SPWTQWSPCS HTCSGKNAEG KQTRVRSILA YNAGEGGVQC PNVSALLEVR SCNDHPCTVY
     HWQTGPWGQC IEDSSFPYTN MSVGVTRPDD GSCAVGMQTR KVICVRVNVG QVPPKKCPES
     LRPDTVRPCL LPCRKDCIVS PYSEWSPCPS TCPGGSNSKK KQFRKRIIIQ VPTNGGQDCP
     EVLVQERECE ARSVCPGYRW KTHKWRRCQL VPWSVRQDSP GAQETCGPGL QFRAISCRKQ
     DGGQADVEAC LKSASPMPPL TQLCHLPCQE DCQLSSWSKF SSCTANCVGV RTRKRTLMGK
     SKKRDQCKNN QMYPLSETQY CPCKKYNAQP VGNWSDCILP ENSRVEGQLG MKVQGDIKEC
     GQGYRYQAMA CYDQDSRLVE TSRCNSHGYI EEACIIPCPS DCKLSEWSNW SRCSKSCGSG
     VKVRSKWLRE KPYNGGRPCP KLDHVNQVQV YEVVPCLSDC GQYVWVAEPW SVWKISNVDL
     RSNCGEGVQT RKIRCMLNTI DGPSEQVEDY LCDPEEMPLG ARNSRLPCPG DCVLSDWGSW
     SRCPLPCSEN RTRERAAFPL RQPGNNKTCP PTTETEPCRK NSNCFHYSYN ITDWSTCQLS
     EKAVCGYGIK TRMLDCVRSD GKSVDPSYCK ELGLDRKLQM NASCVVECPV NCQLSDWSAW
     SECTRSCGLA GKLWRRRTVV QAPQGDGRPC PYQMEQWKPC PVQPCYSWRY STWSECRSEG
     ARCGHGVRFR NVSCFVSDGS GQQDSGLVDD ELCADVELLV DGDAQIILQE ACTIPCPGDC
     YLTDWTVWSP CQLNCINGDD LGFGSVQVRS RAVLAQDPEN LLQCPEQELE ARPCTGGQCF
     EYKWRSGPWR GSSRQVWCER SDGLNVTGGC LLSSKPMADR SCHPPCTKPR SLCTEAGVCG
     CEEGFTEVMT SDGLLDQCTV IPMLEIPTTG DNRADVKTIR GFNPTQPAAS APGRAGRTWF
     LQPFGPDGKL KTWVYGVAAG VFVLLVFIIS MTYLACKKPK KPPRRQMNNR LKPLTLAYDG
     DADM
//