ID   A0A3B3BPB8_ORYME        Unreviewed;       445 AA.
AC   A0A3B3BPB8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Apoptosis inducing factor mitochondria associated 5 {ECO:0000313|Ensembl:ENSOMEP00000007315.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000007315.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000007315.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase family.
CC       {ECO:0000256|ARBA:ARBA00006442}.
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DR   AlphaFoldDB; A0A3B3BPB8; -.
DR   STRING; 30732.ENSOMEP00000007315; -.
DR   PaxDb; 30732-ENSOMEP00000007315; -.
DR   Ensembl; ENSOMET00000004320.1; ENSOMEP00000007315.1; ENSOMEG00000008508.1.
DR   GeneTree; ENSGT00940000166421; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd03478; Rieske_AIFL_N; 1.
DR   Gene3D; 3.30.390.30; -; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 4.
DR   Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR   InterPro; IPR028202; Reductase_C.
DR   InterPro; IPR017941; Rieske_2Fe-2S.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   PANTHER; PTHR43557; APOPTOSIS-INDUCING FACTOR 1; 1.
DR   PANTHER; PTHR43557:SF9; APOPTOSIS-INDUCING FACTOR 3-LIKE; 1.
DR   Pfam; PF07992; Pyr_redox_2; 1.
DR   Pfam; PF14759; Reductase_C; 1.
DR   Pfam; PF00355; Rieske; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
DR   SUPFAM; SSF50022; ISP domain; 1.
DR   PROSITE; PS51296; RIESKE; 1.
PE   3: Inferred from homology;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          1..95
FT                   /note="Rieske"
FT                   /evidence="ECO:0000259|PROSITE:PS51296"
SQ   SEQUENCE   445 AA;  49672 MW;  010301176368D38D CRC64;
     MVCLESDLQD GQMKEVEVGH HSVLLTRYDG KYSALGNQCT HYGAPLSQGV VLGNRVRCPW
     HGSCFNICTG DLEEFPGIDS LPCHKVKIQN SKVYVTVNNK HSYVSSVFVT ELFSPGIASL
     MCAETLRQEK FGGRIIMVSR DHLLPYDKTR LSKVMNVESD TIVLRRMEFY HQYDIEVWLR
     KEALSVDTEK KTVTFDDGLV QNYDQLLIST GCRAKALDVP GTKLDNIKML ETPEDMLSEN
     NVKFYMNDMV TEIKGVNGKV KEVVLKSGKV IPTDVLIVGI GEKNSLLYSF LLWPLTVTLK
     GIYMRTNVPD VFCAGDLASF PLPLAKNKVV NIGHWQMAQA QGRVAALNML GKETELTSVP
     FYWTVLLGKT IRYAGYGEGY TELVMKGNIQ EHKFLALYLK NDEVIAAAGL NFDPAVSAVA
     ERLSSGKVIT KKEAQSDDLS WLQMS
//