ID A0A3B3BQG7_ORYME Unreviewed; 815 AA.
AC A0A3B3BQG7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Extracellular calcium-sensing receptor-like {ECO:0000313|Ensembl:ENSOMEP00000007233.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000007233.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000007233.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B3BQG7; -.
DR Ensembl; ENSOMET00000004463.1; ENSOMEP00000007233.1; ENSOMEG00000008333.1.
DR GeneTree; ENSGT00940000162782; -.
DR OMA; AWITADR; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24061:SF519; EXTRACELLULAR CALCIUM-SENSING RECEPTOR-LIKE; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 552..577
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 589..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 668..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 715..736
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..768
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 780..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 553..815
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 815 AA; 89928 MW; 591CC8023490FCA0 CRC64;
MPSLFKPGDI MIGGIFPIFN KEISNTIVFE REPGGTVCSF DLRAFRWTQV MIFAIEEINK
DPAFLPNVSL GYRILDSCAS PTNALRAAST LAAGPQGIES PCPPAISALI AESGSSQSVA
VAGVLGPFQL PIISYFSTCA CLSNRDKFPT FFRTIPSDYF QAKALAALVK HFGWKWIGAI
QSDNDYGRNG IQAFIEEVKK MGVCVAFVGT VLRTYSMSKI LDVVEMIKQS SVKVILAFVP
EGDFYPLMKE LSRQNITGIQ WIASEAWITA ARPSTPEMFP AFGGTLGFVV QKMAIPDLQS
FLRNINPYAD PNAAFVRDFW EVMFGCRPVS TGIYTGTNKI CEGNETLMNS QDVFFNVTQL
RVSYNVYKAV YAIAHALHEL VFCQSVDRKP ARPCMNVSEI QPQEVTDHIK HVNFRNRFGD
SVFFDQDGDP PASYDIINWQ LDNGKVQHVT VGQFISTQSG TYKLQIDEKK IVWMTGQMVP
KSVCSDVCPM GTRRASIRGK ATCCFDCIPC ADGTISNSTS VECLTCPEDF WSSRQNDHCV
PKKIEFLSYH EPLGICLTAA SLLGTFICSI VFAIFTYHRS TPVVRANNSE LSFLILVSLK
LCFLCSLLFI GQPQLWTCQL RHAVFGISFV LCVSCILVKT MVVLAVFKSS KPGGGANLKW
FGSVQQRGTV LGLTCVQAIV CTVWIISASP TPYANTRYHN DKIIYECVVG STTGFAVLLG
YISLLAIISF LLAFLARNLP DNFNEAKFIT FSMLIFCAVW VAFVPAYVNS PGKYADAVEV
FAILASSFGL LVALFGPKCY IILLKPEKNT RKAIM
//
