ID A0A3B3BQU8_ORYME Unreviewed; 860 AA.
AC A0A3B3BQU8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000007363.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000007363.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B3BQU8; -.
DR STRING; 30732.ENSOMEP00000007363; -.
DR PaxDb; 30732-ENSOMEP00000007363; -.
DR Ensembl; ENSOMET00000004246.1; ENSOMEP00000007363.1; ENSOMEG00000008456.1.
DR GeneTree; ENSGT01050000244874; -.
DR OMA; IFFQYRH; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR CDD; cd06364; PBP1_CaSR; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00980; G_PROTEIN_RECEP_F3_2; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..860
FT /note="G-protein coupled receptors family 3 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017389595"
FT TRANSMEM 588..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 629..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 659..683
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 815..838
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 589..853
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 860 AA; 95734 MW; 6909067429A36D18 CRC64;
MLLLADLLLF FLVVVREGKP TCQTYGTKEL SSFFKEGDIT IGGIFSFHQS PVTASSALEL
NPGSIQCEGL DQGELQYAYT MMFAIEEINN SSELLPDVTL GYRIFDSCPS IPLSIRASLN
LMNAYKGEKS SCDKPSSVHA VIGDTTSTST IGIARTLGPF HIPVISHSAT CACLSNRRDY
PSFFRTIPND IFQSKALAKL VKHFGWSWVG AIRTNNDYGN GGMATFLESA KKEGVCVEYS
VAIYRTDPRQ RFLDVVNIIK KSTSKVIVAF ADGTDLDILF RELHAQSVTG LQWVGSEGWI
TYRQIATPMN YAVVQGAVGF AALSSPIPGL QEFLRNSKPS ITEGNQGLVE LWEMVFNCTL
KYKTEAQDYK PCNGMETLRK VNLPFTDVSD TSLLNNIYKA TYAIAHALNM LINCENEQGP
FENNSCADRK NIQPWQVLYY LSRVNFTTDT GENVFFDDLG DPVARYALVN WQMDETGHTL
FQTIGYYDAS QPEGQQFDVN PGVSAIWAGE NREVPKSICS ESCLPGTYRA FIKGKPICCF
DCIPCAEGEF SNSTNAVNCD KCHPEYKSSE ERTSCDLKAI EFLTFTELMG ILLVAFSVFG
ACLAMFVAVT FYHHRKTPIV KANNSELSFL LLFSLSLCFL CPLTFISRPT KWSCMLRHST
FGIIFVLCMS CVLGKTIVVL MAFRATLPGS NMLKWFGPVQ QRISVLAFTL IQVSICILWL
TINPPYPHKN VKYYKDKVIL ECSLGSSLGF WAVLGYIGLL SLLCFGLALM ARKLPNNFNE
AKFITFSMLI FCAVWLTFIP AYVSSPGKFS VAVEIFAILA SSYGLLCCIF FPKCYIILFK
PEKNTKKHLM GKVTKEKPLN
//
