ID A0A3B3BRS8_ORYME Unreviewed; 477 AA.
AC A0A3B3BRS8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=EGF-like repeat and discoidin I-like domain-containing protein 3 {ECO:0000313|EMBL:KAF6732673.1, ECO:0000313|Ensembl:ENSOMEP00000007989.1};
GN ORFNames=FQA47_011219 {ECO:0000313|EMBL:KAF6732673.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000007989.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000007989.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|EMBL:KAF6732673.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bigg-433 {ECO:0000313|EMBL:KAF6732673.1};
RX PubMed=32938378;
RA Liang P., Saqib H.S.A., Ni X., Shen Y.;
RT "Long-read sequencing and de novo genome assembly of marine medaka (Oryzias
RT melastigma).";
RL BMC Genomics 21:0-0(0).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; WKFB01000184; KAF6732673.1; -; Genomic_DNA.
DR STRING; 30732.ENSOMEP00000007989; -.
DR PaxDb; 30732-ENSOMEP00000007989; -.
DR Ensembl; ENSOMET00000003186.1; ENSOMEP00000007989.1; ENSOMEG00000009145.1.
DR GeneTree; ENSGT00940000156049; -.
DR OMA; YVKTFKV; -.
DR OrthoDB; 3043281at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR Proteomes; UP000646548; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0032101; P:regulation of response to external stimulus; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00057; FA58C; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR46806:SF10; EGF-LIKE REPEAT AND DISCOIDIN I-LIKE DOMAIN-CONTAINING PROTEIN 3 PRECURSOR; 1.
DR PANTHER; PTHR46806; F5/8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 3.
DR Pfam; PF00754; F5_F8_type_C; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00231; FA58C; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01285; FA58C_1; 2.
DR PROSITE; PS01286; FA58C_2; 2.
DR PROSITE; PS50022; FA58C_3; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000646548};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..477
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040589861"
FT DOMAIN 25..63
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 66..110
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 112..148
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 151..307
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DOMAIN 318..475
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
FT DISULFID 34..51
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 53..62
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 100..109
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 138..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 477 AA; 52892 MW; 223DA7977133987E CRC64;
MKHVVDVTAA HLGAIILLVS ISSIRGDFCE VNHCFNGATC VTGVGEEPFI CICSDGFAGD
TCNLTETGPC SPNPCKNDGT CEVIASSRRG DVFSEYICRC PPGFEGVHCQ TNVNDCAKQP
CNNGGTCRDL DGDYTCHCPS PYVGKQCQLR CISLLGMEGG AISESQIYSS SVHYGVLGLQ
RWGPELARLN NQGIVNAWTS AAHDRNPWIE INMQKKMRLT GIITQGASRM GAAEYIKNFK
VASSLDGISY ITYKVEGQRR DKVFVGNSDN DGTKTNLFDP PIVAQYIRII PVVCRRACTL
RMELVGCEIH ASSNTAGCTE ALGMKSRLIS DEQLSASSSF RTWAIDAFTW HPQFARLDKM
GKTNAWSPAH NNRSEWIQVD LERTKRITGI ITQGAKDFGV VQFVSEFKVA YSNDGKSWTV
VKEENTDNEK IFQGNIDNNT HKKNIFEPPF YARYVKIIPW EWHERITLRM ELLGCDD
//
