ID   A0A3B3BT79_ORYME        Unreviewed;       619 AA.
AC   A0A3B3BT79;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=G protein signaling modulator 2, like {ECO:0000313|Ensembl:ENSOMEP00000008002.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000008002.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000008002.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GPSM family.
CC       {ECO:0000256|ARBA:ARBA00006600}.
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DR   AlphaFoldDB; A0A3B3BT79; -.
DR   Ensembl; ENSOMET00000003170.1; ENSOMEP00000008002.1; ENSOMEG00000009214.1.
DR   GeneTree; ENSGT00940000154667; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003109; GoLoco_motif.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR   PANTHER; PTHR45954; LD33695P; 1.
DR   Pfam; PF02188; GoLoco; 2.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 3.
DR   SMART; SM00390; GoLoco; 3.
DR   SMART; SM00028; TPR; 7.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50877; GOLOCO; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803}.
FT   REGION          431..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          529..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        545..571
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   619 AA;  69155 MW;  41B4228CA4AD7E34 CRC64;
     MESSCLDLAL EGERLCKAGD YRAGVSFFEA AIQVGTEDLQ ILSAIYSQLG NAYFHLQEYI
     KALEYHRHDL TLTRAIGDEV GEAKASGNLG NTLKLLGRYD EAVVCCQRHL EITKAIYDKV
     GQARALYNFG NVYHAKGKSI CWSGAKPGEF PEEARTALRK AAHYYEANLN LVMELGDRAA
     QGRTYGNLGN TYYLLGDFEA AIAAHEKRLL IAKEFGDKSA ERRAHCNLGN AHIFLSQFEI
     AANHYKRTLQ LARLLKDRAV EAQACYSLGN TYTLLQDYER AIDYHLKHLV IAQDLKDCVG
     EGRAYWSLGN AHTALGNHEQ AMLFAEKHLE IAKRTGDKSG EMTARMNLAD LRMVVGPKSN
     PSMQYMFPNN RINDPDPIEP QPSHLILPGK SKLDLKNLRF ILYLFSGSSK SNTIKASTKL
     FLFQRLNSKK QKNNKPFAKD QEENQTNYAQ KHQDTVGEDS FFDILSRFQS NRLDDQRCSL
     DSQSHLSLRM ILSHMPFFPA ASEQNTPSQD PGHFLERLAS CQAHRLDDQR ASGSHFPGLH
     LSTCNPPHIP STSSTEPAPP QGSSGSRLND QRCSAPPPKP KGPTVPNEDF FTLILRSQGN
     RMEEQRVPPP ASITLDKPG
//