ID   A0A3B3BWM4_ORYME        Unreviewed;       562 AA.
AC   A0A3B3BWM4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Probable G-protein coupled receptor 22 {ECO:0000313|Ensembl:ENSOMEP00000009207.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000009207.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000009207.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B3BWM4; -.
DR   STRING; 30732.ENSOMEP00000009207; -.
DR   PaxDb; 30732-ENSOMEP00000009207; -.
DR   Ensembl; ENSOMET00000001155.1; ENSOMEP00000009207.1; ENSOMEG00000010407.1.
DR   GeneTree; ENSGT01050000244841; -.
DR   OMA; NSWVEPP; -.
DR   OrthoDB; 2953289at2759; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR   CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   PANTHER; PTHR24241:SF127; G-PROTEIN COUPLED RECEPTOR 22-RELATED; 1.
DR   PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR   Pfam; PF00001; 7tm_1; 2.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        43..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        81..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        437..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        473..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          59..493
FT                   /note="G-protein coupled receptors family 1 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50262"
FT   REGION          302..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        321..337
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..354
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..406
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   562 AA;  60872 MW;  7EC5D62E0F6754B7 CRC64;
     METEGYRDLL ETSDGQGVGL LDGGSEVGVE EGWSEPYPLS FQVSLTTVLM LELVLGFSSN
     LTVLVLYCAQ SNLVDSVSNL VTVNLHVLDI LVCLLCLPLT VAVILLPANE NGVGSLATLC
     CFHEACVTFT SVATAVNVLV ISLDRYDISV RPASRLLTPR RAALLLAAVW AVSLAVFFLP
     FLEGDFFSSA TEEDEDEELE RHSNDSELAT GSTPVYSSFP PSVSQPTPPP SLSHHLQPAW
     QNRTLLCVGG QGYYTGLAMY YHLLLQVPCF FIAVAVMLFT YSRILQALNI RIGSHMMRST
     RAKDSTCRIR CRRQKRKDLS LPTEAASSNQ NPNQNHPPLI PSATPTPTSP PPLSSIPQGV
     SDSGATVTTV STAATTPIAT TPATPASPTP ASASAQTRAS TPLPASSMGV QASVSAIIAL
     RRAVRRHRDR RERQRRVLKM SLIIISTFLG CWAPLSAVNV LILCMGPSDS LVRLRLCFLA
     MAYGTTIFHP LLYAFTRQKL RRALKTRVKK RVVSLLQVDP APSGGTIIHN SWVEGGGQRK
     GRKSRVEASD GTDRCLTDTV RE
//