ID A0A3B3BZ36_ORYME Unreviewed; 411 AA.
AC A0A3B3BZ36;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=ETS transcription factor ELK3 {ECO:0000313|Ensembl:ENSOMEP00000010835.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000010835.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000010835.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR STRING; 30732.ENSOMEP00000010817; -.
DR PaxDb; 30732-ENSOMEP00000010817; -.
DR Ensembl; ENSOMET00000017729.1; ENSOMEP00000010817.1; ENSOMEG00000000296.1.
DR Ensembl; ENSOMET00000032076.1; ENSOMEP00000010835.1; ENSOMEG00000000296.1.
DR GeneTree; ENSGT00940000157129; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF172; ETS DOMAIN-CONTAINING PROTEIN ELK-3; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..411
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040679896"
FT DOMAIN 5..85
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 111..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 261..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 411 AA; 45978 MW; 9D9C4ADC65C4D638 CRC64;
MDSAITLWQF LLQLLLDQTH KHLICWMSTD GEFKLLKSEE VAKLWGLRKN KTNMNYDKLS
RALRYYYDKN IIKKVIGQKF VYKFVSFPEI LKMDPQAVEM GLASGRLPLQ EGKAHELEAE
EEEEVESEEE TQRRTQGALS QQCRSNYIHS GLYSSFSISS LQTQSEFLRA LREHQEEPRS
VIRFGTNERS SPPPVKSESR PSKLLSLPPS SPPTQPGRSW SPTAAEDEEE EDKAADSDQN
AQPLNLSSGH RERALQPPEK RSSDSRNPST NQGDGLPPKS KKPKALEISP PSLLLSGSDI
GSIALNSPAL PSGSLTPAFF AAQTPSGLLL AHSPLLSGIH FWSSLSPVAP LSPARLQGHS
SLFQVRSTQV KKNPKKQSVV FGRHPEHTCY FLVDKRQVKV IWLVFAKQQC L
//
