ID   A0A3B3BZF1_ORYME        Unreviewed;      1050 AA.
AC   A0A3B3BZF1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=GTPase activating Rap/RanGAP domain like 3 {ECO:0000313|Ensembl:ENSOMEP00000010950.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000010950.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000010950.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3BZF1; -.
DR   STRING; 30732.ENSOMEP00000010950; -.
DR   PaxDb; 30732-ENSOMEP00000010950; -.
DR   Ensembl; ENSOMET00000017898.1; ENSOMEP00000010950.1; ENSOMEG00000012232.1.
DR   GeneTree; ENSGT00940000159362; -.
DR   OrthoDB; 25782at2759; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR   PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   SMART; SM00036; CNH; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT   DOMAIN          199..415
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   DOMAIN          503..820
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          827..854
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          952..1024
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        827..850
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        952..989
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        990..1009
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1050 AA;  117726 MW;  6485F47C31B3E16B CRC64;
     MNSDKNVYLG RDKALMRKRA QLLRKGCSFE ITSSASEDLG CRRGDFSRKH YGSVELLISS
     DADGAIQRAG RFRVENGSSD ETSAYTPGTW RRTDVHLENP EYHTRWFFKY FLGKVHQNYV
     GTDAEKNPFF LSVVLSDQNN QRVPQYRAIL WRRSGTLKIS LPYSPTKTLS VKSILSAMNM
     DRFERGPREI LNPEIQKDLL VLEEQEGSVN FKFGVLYAKD GQLTDDEMFS NEMGSENFEK
     FLTLLGDTIT LQGWAGYRGG LDTKNDTTGI KSIYTVYQGH ELMFHVSTML PYSKENKQQV
     ERKRHIGNDI VTIVFQEGDD TSSTFKPSMI RSHFTHIFAL VKYNCQNDSY RLKIFSEESV
     PLFGPPLPSQ PVFTDHQEFR DFLLVKLING EKATLETPTF AQKRQRTLDM LIRSLYQDLT
     PDLHKVPFSP QNMLNRRSFS DVLPESPKSA RKKEEARQAE FVRIGQALKL KTIVRGDAPT
     SLVTTGLCRK EPWESQSFCS TFPYEIVCAD SWGQSLLVAT DTAGVVLLEG SDPALTVAET
     QTLPPVPVFD KTMAVKQMHV LEPQDLLITR ADKGKDARLY VFKLGTIKRS LEEKQLIRGK
     CDCRENKLEK TKGCHLYSIN THHGSELRIV AAIRTKLLLI TRKHPRFSAV ATGADSPVEE
     FQYIREICLC DPPVVMALVD GPTGENDNMI CVAYKHQFDL INESTGDAYR LHHVDANKVN
     FVAAIDVYED GEAGLLLCYN YICYYKKVCP FNGSTPMIQS NTPDFHFSWN QMPNAIVCAF
     PYILAFTTDS IEIRLVVNGN LVYTAVVPEL QLAASRSDIY FVSSAPVSSA SNCSSRDTSS
     QSSPQTPTGY EMPVFPSPLG DDSIRIPYGT KLSQYMSKDA EGEVTCKHIF KIPLCNLVGR
     SIERPLKSPL VNKVLTAPTP AMAAPTPLIS ATHSMSLSRM EIKEIASRTR KELLGLTEEP
     SGKSDSGSVK HRKMSKKNTD EDPKARALTS KNSDSRPTSE SSGADSDIQL HCPSSLEAEP
     EKAVLQEECP PLTSAFTLPT SFEEDVLDLK
//