ID   A0A3B3C459_ORYME        Unreviewed;      1186 AA.
AC   A0A3B3C459;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Protocadherin 7 {ECO:0000313|Ensembl:ENSOMEP00000011847.1};
GN   Name=PCDH7 {ECO:0000313|Ensembl:ENSOMEP00000011847.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000011847.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000011847.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3C459; -.
DR   Ensembl; ENSOMET00000019057.1; ENSOMEP00000011847.1; ENSOMEG00000013194.1.
DR   GeneTree; ENSGT00940000157221; -.
DR   OMA; AFDREHQ; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 7.
DR   Gene3D; 2.60.40.60; Cadherins; 7.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   InterPro; IPR013585; Protocadherin.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF253; PROTOCADHERIN-7; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF08374; Protocadherin; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 7.
DR   SUPFAM; SSF49313; Cadherin-like; 7.
DR   PROSITE; PS00232; CADHERIN_1; 4.
DR   PROSITE; PS50268; CADHERIN_2; 7.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        844..867
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          49..138
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          139..275
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          276..382
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          399..501
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          502..605
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          606..708
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          719..815
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   REGION          178..201
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          874..954
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1051..1100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1140..1172
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..897
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1067..1100
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1186 AA;  130097 MW;  F17B4C0CAFF0A403 CRC64;
     MRTTAAVDCL YYCMLILQLV HQPDAKQVLR YRLAEEGPAD VRVGNVAGDL GMVAGSREVT
     FTLESGSEFF KIDNITGELT TNEKRIDREK LQQCQMIFDE NECFIDFEVS VIGPAQSWVD
     LFEGKVTILD INDNTPSFPS PVLTLSVEEN RPIGTLYLLP TATDRDFGRN GIERYELIQD
     NGENSRRSGS SGDSYSGKRR FEEGASRSSV FELQVADTTD GEKQPQLIIK GALDREQRDS
     YELTLRVRDG GDPPRSSQAI LRVMITDVND NNPRFEKSVY EADLPENSSP GSPILQLKAA
     DADVGVNGQI EYVFGAATES VRRLLRLDES TGWLSVLHRI DREEVSQLRF SVMARDRGQP
     PKMDKATVVL NIKDENDNVP AIEIRKIGRI FLKDGVANVA EDVVVDTPIA LVQVSDRDQG
     ENGIVTCTVV GDVPFQLKPA SEMDEQNKKK YFLHTSAPLD YETTKEYNVV IVAVDSGSPS
     LTSNNSLLVK VGDTNDNPPT FSKNVVQVSF PENNAPGERV TTVTAADADS GKNAEIAYSL
     DSSVNGIFSI DADSGDIRVN TNLDREQKER YEFKVIAKDK GINTLQGSAT VVVLVDDKND
     NEPKFMQDVF TFYVKENLDP NSPVGMVTVI DADKGQNAEM GLFIEEEEEI FSIENETGTI
     FSTLSFDREQ KTTYTFRVKA VDGGDPPRSA TATVSLFVMD ENDNAPTVTF PINSSYTLLP
     PSSTVRTVVR TVIATDTDTG INADLNYSII GGNPFKLFEI DGATGVISLM AKLEQKHYGL
     HRLVIQVNDN GQPSQSTTTL VHVYVNETLS NSTIVEALVA RSLSTSLNTN IAGDPNYDLS
     KQRLSIVIGV VSGIMTVILI ILVVVMARYC RPKNKNGYEA GKKDHEDFFT PQQHEKSKKP
     KKDKKKQKSK QPLYSSIVTV EASKPNGQRY DGVSEKLSDS PGMGRYRSVN GGPGSPDLAR
     HYKSSSPLPT VQLHPQSPTA GKKHQAVQDL PPANTFVGTG DNISLGSDHC SEYSTQTINK
     YNKQEIKNIK NSRPLPDVAM TGKCTRECDE YGHSDSCWMP VRTSPERRPS KPTTNPQQPK
     LSTFMTGNGS SSSSAEQPGS QETLAMAAMA NGDPTAAHMM GDRNRNLLNK KMASSSSYEA
     FGSPSYGSPG GGEEVLGHPT EEIPLAPTGE YKPTTCGTLT RREVYL
//