ID A0A3B3C4T2_ORYME Unreviewed; 733 AA.
AC A0A3B3C4T2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25-like {ECO:0000313|Ensembl:ENSOMEP00000012072.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000012072.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000012072.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3C4T2; -.
DR STRING; 30732.ENSOMEP00000012072; -.
DR PaxDb; 30732-ENSOMEP00000012072; -.
DR Ensembl; ENSOMET00000019322.1; ENSOMEP00000012072.1; ENSOMEG00000013430.1.
DR GeneTree; ENSGT00940000154294; -.
DR OMA; RWYWEVN; -.
DR OrthoDB; 5347036at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19756; Bbox2; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF36; E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 11..53
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 335..371
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 538..733
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 66..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 372..406
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 137..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..194
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..247
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 81020 MW; DCA7F6FFFF71DE19 CRC64;
MGAVLDTPAT CPLCNESTRD PVVLKCSHRF CQRCIGDLWS VTPNGPFHCP EWRCKTVYQS
LPFDSSLIRP PTPARPVQAR GSAGTSNNVE QTSSDQRHKR PSLTSRLLGK RKASSQIPDE
PVSKRSELAC GPSGDRKQPA INTSQKPDDA AGVGTSQETC GGPRARSDQG DGLPENESVG
PRDTLKKTAE SVEESDTSSE IDVCDAPLVS PKQATHTPSK KPATASSSDC SGGPSGQGLS
RVNQVGGASP VSPKKPKSAS GSPINVAIFL RPENKPSTPV PCHYCPKARC QPAVNTCLVC
GASMCQEHLR PHLESPVFQS HTLVSPVEDI SLWKCQEHQE VNRIYCRQCE MCVCTVCTLI
GSHRDHVCIS IREAERELRA NLKEEIKQLQ DTEEQVKTRV SQLGEKKETS RIVLTEAQES
VKQQYGAIRE ALDQEEQSAL QCIFKEERRV LGGLEDKLSF LQKTLQSIQN GLHTLEGLAD
SKGDKGVKDQ LFIMEYCKVS QMVSGVGSCV ELFESPEEVN IDRLNSLKTW TEKRLDTVII
NMPGKDRDLY RLQYGIIPVL DEDTAHPKLQ LSDNNRKVSY SETQQVYADH ESRFTSFPQV
LASDALEKGR WYWEVNVPAD DGRWKVGLCE SQMERKGQKD SSRLGFNSHS WCLAYDKKRL
EALHNKESIP VKTDDLQTIG VLLDFEDGSL SFFNATPGGS LVLLHSYKHS FSSPLHPAFS
VSKTHLAMCD LFQ
//
