ID   A0A3B3C7K5_ORYME        Unreviewed;       847 AA.
AC   A0A3B3C7K5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000013273.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000013273.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3C7K5; -.
DR   STRING; 30732.ENSOMEP00000013273; -.
DR   PaxDb; 30732-ENSOMEP00000013273; -.
DR   Ensembl; ENSOMET00000020865.1; ENSOMEP00000013273.1; ENSOMEG00000014719.1.
DR   GeneTree; ENSGT00940000164983; -.
DR   OMA; PEMQSHC; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 5.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR032455; Cadherin_C.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF236; PROTOCADHERIN CLUSTER 1 GAMMA 26-RELATED; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   Pfam; PF16492; Cadherin_C_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 6.
DR   SUPFAM; SSF49313; Cadherin-like; 6.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 6.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..847
FT                   /note="Cadherin domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017255805"
FT   TRANSMEM        687..711
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          21..127
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          128..236
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          237..344
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          353..449
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          450..559
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          575..670
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   847 AA;  93320 MW;  9A3F5BD6D875122F CRC64;
     MKDMGWQALW WHHFFLLWST IDAQTRYSIP EELKHGSVVG NLAKDLGLTL TEISERALRV
     ASESGEQYFR VDAGRGELLV NDRIDREALC GQSASCVLPL QLVLEKPLSL HRIEVEIQDI
     NDNPPKFYTE ELFLNISETA VVGTRFPLES AEDSDVGGNS VKSYTLTKNE CFTLKMKEVE
     DGKTVPELVL EKSLDREIKA VHQLRLTALD GGNPVKSGTS TITITVLDVN DNFPVFEKNS
     YRVSLLENTA KGSFVIKVAA TDADEGPNGE IEFSFGARTP DSVLTLFNIN PSSGEIILKG
     DLDYERETSY KIEITAKDKG SPEMQSHCRL QIDVIDVNDN KPEIILTSEP QPVREDAPGG
     TVVALLNVRD ADSVNNSKVT LQISKGSPFK LKTSFSNNYA LITSGPLDRE KVSDYHVEIT
     ATDSGSPPLS SKRIVSVRIT DVNDNPPVFT QKSYNVYLKE NGVPGSILFS VSASDLDSGE
     NAKISYSILD SKVQDVSVSS YVYMNSENGS IYSMHSFDYE KLKVFEIHVQ AKDQGSPSLS
     SNATVHVFIL DQNDNAPAVI YPSSAALGSL SHQRMPRSAK AGHLVTKVTA VDADSGHNAW
     ISYRLAEATD ASLFSVNLYT GEVRTKRAVS EQDDSSQRLI LEIKDDGEPL QSATVTVSIL
     LEDALHEPIS ELRLHKASEP SKKSGRITLY LILSLASVSV LSLLTFVILA VKCMRSSRSS
     GSCCCMRRQD SEDYKNPNRN LQIQLNTDGP IKYVEVLGGD MMSQSQSFRS CMSPMSEYSD
     FTLIKPSSTT DFKEVISVLD ASLPDSTWTF ESQQVTPNRW TATSRVSKAE THTAVNHSGF
     AKYKIKA
//