ID   A0A3B3C8T3_ORYME        Unreviewed;       798 AA.
AC   A0A3B3C8T3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Heterogeneous nuclear ribonucleoprotein U {ECO:0000313|Ensembl:ENSOMEP00000013497.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000013497.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000013497.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3B3C8T3; -.
DR   STRING; 30732.ENSOMEP00000013497; -.
DR   PaxDb; 30732-ENSOMEP00000013497; -.
DR   Ensembl; ENSOMET00000021125.1; ENSOMEP00000013497.1; ENSOMEG00000014951.1.
DR   GeneTree; ENSGT00940000156546; -.
DR   Proteomes; UP000261560; Unplaced.
DR   CDD; cd12884; SPRY_hnRNP; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035778; SPRY_hnRNP_U.
DR   PANTHER; PTHR12381:SF11; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U; 1.
DR   PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF02037; SAP; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   SMART; SM00513; SAP; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50800; SAP; 1.
PE   4: Predicted;
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          6..40
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   DOMAIN          181..377
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          45..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          583..798
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..83
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..98
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..119
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..161
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        593..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..663
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        728..787
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   798 AA;  87685 MW;  32CAC2E82A85D391 CRC64;
     MSTINVKKLK VNELKDELKK RNLSDKGLKA ELMDRLQAAL DEEALVGDSS AAQEGAEEEA
     FEQAAEQEVM GEEEEGPVEE SMEANEEEQA HGDEGNGVAD DEDMGEGEEG DEDDEMLKGD
     VDDMEKIDTE DGEPGEPAAD GDADKDTNAD QKNKKGVKRR REEHGRGYFE FIEENKYSCA
     SFKSPVPPLE EEDEQFDDTK VCLDTYNCDL HFKVSRDRYS ASSLTMESFA YLWSGGKANY
     GVNKGRACFE MKITEKIPVK HISSKNMEIH DVQVGWSLVT GSLLLGEEEF SYAYSGKAKK
     TTNCVTEDFG ETFEENDVIC CLIDFEGDEV VLSFSKNGGE PAVAFQVKKD SLNGQALFPH
     VMCHNCAVEF NFGQMETPYF PEVEGYTFLQ KIPVSDRVCG LKGPQTKADC EIIVMVGLPG
     SGKTTWVKTH VQQNPGKYYI LGSDTIVDKM MINSLKRQSK DITKLTAISQ RAPLFLGKFI
     EIAARKKRNY ILDHTNLSAP GQKRKMCLFA GFQRKAVVVC PSDDDYKQRV QKKVESDSKE
     VPEHALLKMK GFYALPEEGE SFSEVIYAEL PKDEASKLLE QYKEESKTAL PAEKKPNQGS
     TTPKRGGGGQ RSGNRGGKNQ FGRSGPGQRG GGRGGFQNRG NFRGPPAPRG GFSRPPRGFL
     PPPAFRGGFP NRGNFSRGGG PIPSLAVSHR GGSMRGNMGP RGGPMSRGGP MNRGNMGRGG
     GGNMNRGGNR GHHSQFQPRG GNRGNFGNKN RDFGNNRNSG GFGNRNGMDK AQAFNQSWQQ
     GVSTPADFSP SLDYFYAE
//