ID A0A3B3C925_ORYME Unreviewed; 1862 AA.
AC A0A3B3C925;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=CHD9 {ECO:0000313|Ensembl:ENSOMEP00000014431.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000014431.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000014431.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR STRING; 30732.ENSOMEP00000014431; -.
DR PaxDb; 30732-ENSOMEP00000014431; -.
DR Ensembl; ENSOMET00000022326.1; ENSOMEP00000014431.1; ENSOMEG00000015978.1.
DR GeneTree; ENSGT00940000155706; -.
DR OMA; WIEASHK; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR CDD; cd18663; CD2_tandem_CHD5-9_like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR46850; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9; 1.
DR PANTHER; PTHR46850:SF1; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9; 1.
DR Pfam; PF00385; Chromo; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50013; CHROMO_2; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 754..820
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 853..1027
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 1167..1323
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 366..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 515..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1453..1474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..503
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 588..629
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1862 AA; 211401 MW; 965A5B174297B153 CRC64;
MDFFDDPNLF EGGLEGLEED GFPPGPSLVD ELNFSADFEP LQVETLGPGK HQDMMPAVSA
QQALPNYSQQ MGHYAGIKPQ NPIAQAFSGP QSAGCGIMAD QLGQFHNPAI GQVPQSNGLF
CNSGSPMWGN QDQNGNVFHP LSQQQQQLCH QQLHNQQLHV QQHAQQQNLS LPHTQQPIQH
QITQREAQFY SRVHPSKSYL ENTSLSRTPL QIQQQDSYHA LRRGQAFPGP GLEDSILSHQ
THSSSRVQSL STCSVTSANA YQPALYPAYP GESEIPSFSQ LSSSTATVSG PTATSSLTST
LPGLSGAACQ FQSPALMRQL HTKTTINQAD ECSFQVLGCS VETQKNCKSS GMLDETMKCY
PGIGRPLPSE QPQRRGAINT NGYQALGDGL LPSEAQDSEL ENLEPTDLLP DLLPQLEDAF
KAESWIEASH KGGEDSKLTS IEYKAEKVSF FFFLQLKSNS SSSSSSSSSS SSSSSSSSSP
SEKRVPRRTH QQMESNLQEK QEKANRIISE AIAKARQRGE KNIPRVMSPE SFPSSSAQFK
AHRDRGHKGN GKARSKDKSS KRACIVQSKP KQKAKIGKIV IKIGKKKKRK PESSEEESDD
DPPLRHTSKD DDSKRRSNRQ VKRKKYTEEL ETRLSDEEVK VIVKAKKTNT AASKQPSVQL
FVENPTEEDA AIVDKIMSSR MAKKEVNTCL SIRFYSFVII FFFNSYLHCE WATEQQLEKD
KRIQQKIKRF KMKQAQRALF FADMEEEPFN PDYLEVDRVL EVSYCEDKDT GQEVVYYLVK
WCSLPYEDST WELKDDVDQS KIEEFEQLQA AKPDSRRVER PPANLWKKKE HSREYRNGNM
LRDYQLEGVN WLLFNWYNRR NCILADEMGL GKTIQSITFL EEIHRIGIKA PFLIIAPLST
IANWEREFHT WTHLNVIVYH GSVVSRQMLQ QYEMYFRDAQ GRAIRGAYRF QAVITTFEMI
LGGCPELNAI EWRCVIIDEA HRLKNKNCKL LEGFKLMNLE HKVLLTGTPL QNTVEELFSL
LHFLEPTRFP SENTFMQEFG DLKTEEQVQK LQGILKPMML RRLKEDVEKK LAPKEETIIE
VELTNIQKKY YRAILEKNFS FLAKGAGQAN MPNLVNTMME LRKCCNHPYL IKGAEEKILE
DFREVYNPSA PDYHLQAMVQ SAGKLVLIDK LLPKMKAGGH KVLIFSQMVR CLDILEDYLI
QRRYLYERID GRVRGNLRQA AIDRFSKPDS DRFVFLLCTR AGGLGINLTA ADTCIIFDSD
WNPQNDLQAQ ARCHRIGQNK AVKVYRLITR NSYEREMFDR ASLKLGLDKA VLQSMSGRDN
SLGGGSGGGQ QLSKKEIEDL LRRGAYGAIM DEEDEGAKFC EEDIDQILQR RTKTITIESE
GHLTTVMNTG HLCLLASFVA SGNRTDISLD DPNFWDKWAK KADIDMEMVN GRNSLVIDTP
RVRKQTRPFS ATKDELAELS EGESDGDETK PKLRRNDRLN SYGRTECFRV EKNLLVYGWG
RWKDILNHGR FKKQLTEWDV ESICRALLAY CLVHYRGDDK IKSFMWDLIA PTEDGRTKEL
QNHLGLSAPV PRGRKGKKMK TQSSSFDIHK AEWLRKHNPE HILLDDGYKK HLKHHCNKVL
LRVRMLYYLK QEVIGSLAQK VLDGVDSSEI KIWVPDPDHS ELPALWWDAI ADKCLLLGIF
KHGYEKYNTI RADPTLCFLE RVGRPDEKAI AAEQRANDLM DGDVDDPEYK PAPALLKDDM
EDDASSPGDL VVSDNAGDAA PVMEGQTAYW PSPSILTARL RRLITASQRF TKTRQIMHIH
QAQSQTQAVS QQPMVLSTAF CPLPPTLNDT LNPKMAAKIE RQQRYIRSSN QLNMCKDNNT
FF
//
