ID   A0A3B3C9J7_ORYME        Unreviewed;       602 AA.
AC   A0A3B3C9J7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Basic helix-loop-helix ARNT-like protein 1 {ECO:0000256|ARBA:ARBA00041169};
DE   AltName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 1 {ECO:0000256|ARBA:ARBA00042144};
DE   AltName: Full=Brain and muscle ARNT-like 1 {ECO:0000256|ARBA:ARBA00041751};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000014601.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000014601.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus, PML body {ECO:0000256|ARBA:ARBA00004322}.
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DR   AlphaFoldDB; A0A3B3C9J7; -.
DR   Ensembl; ENSOMET00000022529.1; ENSOMEP00000014601.1; ENSOMEG00000016170.1.
DR   GeneTree; ENSGT00940000157523; -.
DR   OMA; MEVQEFC; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
DR   GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd11438; bHLH-PAS_ARNTL_PASD3; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR001067; Nuc_translocat.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR23042:SF52; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 1; 1.
DR   PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR   Pfam; PF00010; HLH; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF14598; PAS_11; 1.
DR   PRINTS; PR00785; NCTRNSLOCATR.
DR   SMART; SM00353; HLH; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50888; BHLH; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          55..108
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   DOMAIN          126..191
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          330..379
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          451..472
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          489..530
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..512
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   602 AA;  66355 MW;  A4776AEBC884E2EE CRC64;
     MADQRMDISS TITDFMSPGS TDLISSSIST PGMDYTRKRK GSTTDYHDQQ GRIKNAREAH
     SQIEKRRRDK MNSFIDELAS LVPTCNAMSR KLDKLTVLRM AVQHMKTLRG AANPYTEANY
     KPSFLSDDEL KHLILRAADG FLFVVGCDRG KILFVSESVF KILNYSQNDL IGQSLFDYLH
     PKDIAKVKEQ LSSSDTAPRE RLIDAKTGLP VKTDITPGPS RLCSGARRSF FCRMKCNRPS
     VKVEDKDFPS TCSKKKADRK SFCTIHSTGY LKSWPPTKMG LDEDNEPDNE GCNLSCLVAI
     GRLHPHIVPQ PSPADIRVKP TEYVSRHAID GKFVFVDQRA TAILAYLPQE LLGTSFYEYF
     HQDDINHLAE CHRQVLQMRE KINTNCYKFK IKDGSFITLR SRWFSFMNPW TKEVEYIVST
     NTVVSCPMME GSDYPQSAAS PQSMESVLIS EGGGRRALPT VPGIPGGTRA GAGKIGRMIA
     EEVMEFQKIR GSSPSSCGSS PLNKTSTPPP DSCSPGGKKI QNGGTPELPS TGIIPGPDSV
     GYPYSNQSIM SDNSHLSLDI MDEPGSSSPS NDEAAMAVIM SLLEADAGLG GPVDFSDLPW
     PL
//