ID A0A3B3CAT5_ORYME Unreviewed; 1141 AA.
AC A0A3B3CAT5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Protocadherin-17 {ECO:0000313|EMBL:KAF6725479.1, ECO:0000313|Ensembl:ENSOMEP00000014418.1};
GN ORFNames=FQA47_008302 {ECO:0000313|EMBL:KAF6725479.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000014418.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000014418.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|EMBL:KAF6725479.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Bigg-433 {ECO:0000313|EMBL:KAF6725479.1};
RX PubMed=32938378;
RA Liang P., Saqib H.S.A., Ni X., Shen Y.;
RT "Long-read sequencing and de novo genome assembly of marine medaka (Oryzias
RT melastigma).";
RL BMC Genomics 21:0-0(0).
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DR EMBL; WKFB01000360; KAF6725479.1; -; Genomic_DNA.
DR STRING; 30732.ENSOMEP00000014418; -.
DR PaxDb; 30732-ENSOMEP00000014418; -.
DR Ensembl; ENSOMET00000022307.1; ENSOMEP00000014418.1; ENSOMEG00000015923.1.
DR GeneTree; ENSGT00940000156894; -.
DR OMA; CYVPDRI; -.
DR OrthoDB; 4259465at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR Proteomes; UP000646548; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0048675; P:axon extension; IEA:Ensembl.
DR GO; GO:0007411; P:axon guidance; IEA:Ensembl.
DR GO; GO:0060219; P:camera-type eye photoreceptor cell differentiation; IEA:Ensembl.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF41; PROTOCADHERIN-17; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000646548};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1141
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040589955"
FT TRANSMEM 685..707
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..128
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 129..239
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 240..347
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 349..453
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 454..563
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 569..675
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 816..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1009..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..858
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 859..878
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1030
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1141 AA; 125619 MW; D79379F60418AE64 CRC64;
MHLSIFFFLL LWAQAQTLKN LNYSVPEEQG PGTVIGNIAK DARLGLEQIG QGGQGKKANF
RVLENSAPHL IDVDPQSGLL YTKQRIDRET LCKRNPKCQL SMEVFANDKE ICMIKIDIQD
INDNSPVFPS DQIDIDISEN AVPGTRFPLT SAHDPDAGEN GLKTYQITRD DYNLFSLEVK
SRGDGTKFPE LVIQRPLDRE ERSHHTLILS ATDGGEYPRS GTMQINVKVI DSNDNSPVFD
PPSYVVEIPE NSTPGKVLID LNATDPDEGN NGQIVYSFSG YAPERIRELF SIDSRTGVIK
IQGEIDYEES PVIEIDVQAK DLGPNPIPGH CKVTVKVLDR NDNWPSIGFV SVRQGAISEA
APPGTVIALV RVTDKDSGRN GQLQCRVLGN VPFKLEENYD NFYTVVTERP LDREMQDEYN
VTIVAKDNGI PPLNSTKSFT VKILDENDNV PRFTKSVYIL QISENNIPGE YLGSVLAHDP
DLGQNGTVYY SIVNSNVSGG DVNTYVNVNA ANGAIYAVRS FNYEQIKYFD FKVLAKDAGS
PHLESNATVR ISVQDVNDNI PVIVLPLLQN DTAEIHVPRN VGVGYIVTTV RAVDNDYGES
GRLTYEISDG NEEHLFEIDP VTGEVRTAHS FWEDVSPIVE LIIRVSDHGK PTLTAAARLI
IKASNGRPPD GLPHIKDNQN WDTSLPLIVT LSIISLMLLA AMVTIAIKCK RENKEIRTYN
CRIAEYSHPQ LGKGKKKKIN KNDIMLVQSE VEERDAMNVM NVVSSPSLAT SPMYFDYQTR
LPLSSPRSEV MYLKPTTNNL SVPQGHVGCH TSFTGPVTST TDTPTNRMSI IQTDNFPTEP
NYMGSRQQFV QSSSTFKDPE RASLRDSGHG DSDQADSDQD TNKGSCCDMS AKEALKLKAV
GVKPPPLEQD EDCVNCTEEC RVLGHSDRCW MPQFPAGGNQ AEGIDYRNNM FVPAGMETVP
ETETYEAVNP NGKKTFCTFG KDRRDHTILV ANVKPYLKAK RALSPLLQEV PSASTSPSKG
CSTMSPCSSV KSPADGAEGK PPPASCSGHY GPPDGQYLSP TKQTRDQLIY PSLPPSDPVA
KVLAEARSRI SQEAAAEMEC VLEQAEPNVS RDGMDADQVV RDIDKLLQDC RGNEATGTLR
K
//
