ID A0A3B3CDA2_ORYME Unreviewed; 907 AA.
AC A0A3B3CDA2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Zinc fingers and homeoboxes protein 1 {ECO:0000256|ARBA:ARBA00040117};
GN Name=ZHX1 {ECO:0000313|Ensembl:ENSOMEP00000015901.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000015901.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000015901.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
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DR AlphaFoldDB; A0A3B3CDA2; -.
DR STRING; 30732.ENSOMEP00000015901; -.
DR PaxDb; 30732-ENSOMEP00000015901; -.
DR Ensembl; ENSOMET00000024232.1; ENSOMEP00000015901.1; ENSOMEG00000017537.1.
DR GeneTree; ENSGT00950000182893; -.
DR OMA; HHLSATN; -.
DR OrthoDB; 5350395at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 5.
DR Gene3D; 1.10.10.60; Homeodomain-like; 5.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR024578; Homez_homeobox_dom.
DR PANTHER; PTHR15467:SF4; ZINC FINGERS AND HOMEOBOXES PROTEIN 1; 1.
DR PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR Pfam; PF00046; Homeodomain; 4.
DR Pfam; PF11569; Homez; 1.
DR SMART; SM00389; HOX; 5.
DR SUPFAM; SSF46689; Homeodomain-like; 5.
DR PROSITE; PS50071; HOMEOBOX_2; 4.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}.
FT DOMAIN 265..308
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 428..488
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 560..604
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 659..719
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 267..309
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 430..489
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 562..605
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 661..720
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..668
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 834..907
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 393..431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..668
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..765
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..889
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 890..907
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 907 AA; 99900 MW; 9B7CCA7C0573C9F3 CRC64;
MSSRRKSTTP CMVLPSDVLE PEIAEDKTDR AKEKEANDED KEETVKEGKE QGSAAEELGQ
VVVVVPTPPA ADEASASAVE CNEEAECSLR SGPADPHEDS SGDSSLQDQQ KDSPGEGGAD
PAAVSAISLS KTPIMRLRTK SEPKRIAVSL KSVDEIAEGL AAADERELGA ELEPIEAPLG
PMTPVEMFLH DSVKFGGGSF LYSPPSEQQR KSSVLNPTVV PAGLAQVLSA FQAQQSAAAA
SHPQLLIPVS SIPSYSAAMD TNPLLCSAYK KFPYPSTAEI SNLAVQTQFT EEQIKVWLSA
QRLKHGVSWT PEEVEEARRK QFNGTVHTVP QTITVIPAHQ LSAAANGLQS ILQTCQIVGQ
PGLVFTQVCP GGPLPVTNPI TLTVTGLPTQ SQSAIRSCQP SPSNSELKRA TTIQPPSLSP
QENSALSADN FNMRPKKSKE QLAELKASYM KNHFASDTEI ARLMKITNLT KGEIKKWFSD
TRYNQRNSKN SHVIIFHDGG PREGSSFSSA ANTPIVIDSS DETPTSPHPP HTPPVKEKET
RPKTWNPFPD FTLQKFKEKT PEQLVVLEES FERSSTPTDE ELSRLRTETK LTRREIDAWF
SERRKVPSAS SSFPDSERGK VEADGTEEAD SYSPSASSSR KDTQTLPGSR NKRLPGYSKK
DIRDKTKKTP EQLHILKCAF VRTQWPTPEE YDQLSEESGL PRPYIVSWFG DSRYSWKNGN
LKWFFQYQSG GVERPSGGSG GKLGGGRKRR GRNRGWGRSR SRKQPKRSSY SSADYNKCPP
SKKFKTGKDI LKDYYLKHHF LNEQDLDELV TKTNMSYEQV REWFAEVQKR LDTGSDPFQE
LPTGRAGGDK RGELGETSTP SEEQTSPGMG DEDDDDDAEE DDGEDTDDSE VWEPSRSVKK
SLSVSED
//
