ID A0A3B3CIG5_ORYME Unreviewed; 4514 AA.
AC A0A3B3CIG5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Plectin-like {ECO:0000313|Ensembl:ENSOMEP00000017658.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000017658.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000017658.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSOMET00000026443.1; ENSOMEP00000017658.1; ENSOMEG00000019466.1.
DR GeneTree; ENSGT00940000162855; -.
DR OMA; QQDESEC; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.1060; -; 1.
DR Gene3D; 1.20.58.60; -; 5.
DR Gene3D; 3.30.160.780; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 3.90.1290.10; Plakin repeat; 6.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR041573; Desmoplakin_Spectrin-like.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF20; PLECTIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF00681; Plectin; 16.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF18373; Spectrin_2; 1.
DR Pfam; PF21020; Spectrin_4; 1.
DR Pfam; PF21097; SR_plectin_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00250; PLEC; 33.
DR SMART; SM00150; SPEC; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF75399; Plakin repeat; 7.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 20..123
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 136..241
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 788..845
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1470..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1630..1661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1980..2043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2060..2155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2432..2454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2502..2544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4225..4265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4455..4514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 741..771
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1102..1150
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1222..1252
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1980..2032
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2060..2126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2134..2155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2432..2447
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4225..4258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4514 AA; 516453 MW; 82D3C9EC194FEEB8 CRC64;
MDPTRSIQHE ICSLKDERDR VQKKTFTKWV NKHLIKAQRH ITDLYEDLRD GHNLISLLEV
LSGETLPREK GRMRFHKLQN VQIALDFLKH RQVKLVNIRN DDIADGNPKL TLGLIWTIIL
HFQISDIQVK GQSDDMTAKE RLLLWSQRMV EGYQGLRCDN FTTSWRDGRL FSAIIHRHRP
ALIDMNQVYR QTNQENLEQA FSVAERELGV TRLLDPEDVD VPHPDEKSII TYVSSLYDAM
PRVPDTQDGV NANELELRWQ EYYEVVTMLL QWIRHHILVF EEKKFPTSYE EIEVLWRQFL
KFKETELPAK EADKNRSKHI FKSFEGEVKA GHVKVPPGYH PFDVEKEWGR LHVGILERER
LLRTEFERME RLQRIVGKVQ TESGVCEEQL NQVETLLQAD VRMMSSGKPP QHTAEVEADL
EKAEGMIRFL FNDVQLLKDG RHLQAEQMYR RVYRLHERLV NLRSEYNLRL KSGVAASQIP
MTQIHTVQVL QQSSKSARPE LDEVTLRYAH DLLGWVEENQ RRVDEGEWGS DLANVESQLG
SHRGLHQSVE EFRSKIERAK ADEGQISPVS KPAYREYLGK LELQYGKLLT ASKARLRSLV
ELHTFVSAAT KELMWLNEKE EEEVNYDWSE RNTNMVSKKD NYSGLMRELE LREKKVNGVQ
ATGDKLLRDG HPARKTIEAF TAALQTQWSW ILQLCCCIET HLKENTAYFQ FFADVKEAEE
KMKKMQDTMR RKYTCDRSVT VTRLEDLLQD AADEKEQLAE FKTHLEGLKR KANTIVQLKP
RNPTTPIKGK LPIQAVCDFK QMEITVHRGD ECALLNNTQP HKWRVVNNKG SEASVPSICF
LVPPTNKDAV NSVAGLDGNL QRLHGMWQTM FVDLKSLLSW QYLMRDIHII NTWNVSMFKT
LRVEEYRLAL RNLEQHYQEF LRDSQDSQMF GAEDRLQVES NYKRANQHFH SLVSTAEQGE
QDESVCRTYL TKIKDLRLQL ESCENRTVTR LRQPVEREAL RACALKTAEQ MKVQSELEGL
KKDLSSIAEK TEEILASPQP SSSAPMLRSE LDVTLKKMEH VYGLSSVYLD KLKTIDVVIR
NTKDTEETLK NYETCLRDVR KVPNEEREVE DQRSQLKSMR AEAEADQAVM DRLQDELQRA
TTINDKMMRI HSERDAELEH YRLQVGGLLE RWQAVFAQID LRQRELDFLS SKMKSYKESF
DWLTRWLAEA RQKQENIQAK PINSSKALKE QLAEEKKLLE EIKKNKDEID NCQISAKAYI
DSIKDYELLI LTYKALQDPL ASPLKKPKVE CASDSVIQEY VTLRTRYSEL LTLTSQYIKF
ITDTQSRLEE DEKASEKLKE EERRKMAQME AELEKQKQLA ETQTQFVAKA EREADELKLK
MKEEANKRQD VAVVAETQKQ NIQQELQHLK SLSEQEIKTK SQQLEEALLS RTKIEEEIHL
IRIQLETTVK QKSTAENELQ MLRDKAAEAE RLRKAAQEEA ERLRRQVAEE AQKKKNAEDE
LKRKSEAEKD AAKQKQKALE DLQKFKMQAE EAERRVKQAE DEKLRQIKVV EEVTLKSSAT
DFQTKSMPMA QKATELEESL RKEQGTVLQL QVEADQLRKQ QEEANKAREQ AEKELEMWRQ
KANEALRLRL KAEEEAQKKT QAQEEAERQK LEAEQDAKRR AKVEEMALKQ KENAERELEK
QRTFAEQIAQ QKLSAEEECI RLKADFEHAK QQRSLLDEEL QRLKNEVSAA ENQRKQLEEE
LAKVRQEMDS VLQMKIQAEK EVLSKNEKSK QLLESEALKM KQLAEEATRL RAVAEEAKKQ
RQIAEEEAAK QRAEAEKILK EKLAAINEAT RLKTEAEIAL KAKEAENDRL KRKAEEEAYQ
RKLLEDQAAQ HKHEIEEKIT QLKSSSDSEL ERKKNIVEET LRQKKVVEEE IHIIRINFEK
ASKEKSDLET DLKKLKSLAD ETQKSKIKAE EEAEKLKRLA AEEEKKRKEA EEKVKRITAA
EEEAARQWKA AQEEVERLKK KAAEANEHRD KAEKETERQV ILAKEAAQKR SAAEQKAQDV
LSKNQQDILA QDKLKEEFEK AQKLAEAAQK AKEKAEKEAN LLRQQAEEAE KQKKAAEDEA
AKQAKAQKDA EKLRKEAEEE ASKRAAAEAA ALKQKQQADK EMDKHKKDAE QALKQKAQVE
KELGMVKLQL EQADEQKALL DTELQRLKDE VSDAIKKKKE VEDELSKVRS QMDELAEVKR
KIEEENRCLI QKDKDNTQKL LLEEAEKMKT LAKEAARLSV EAEDAARQRQ LAESDLAEQR
AQAEKMLQEK MQAIQEATKL KAEAEELQKL KEEAQEKAKQ LQEDKKLIQQ RLEQETEGFH
KSLEAERKRQ SELSAEAKKL KLKLKELSGA QAKAEEEVAK FKKQADEAKS QLKETEKQAS
EVVVQKLETQ RLQSTREADD LRKAITDLEK EKEKLKNQTE DLQKRSEQMA TDQQQQIEQQ
KAILKQSFLS DKELLLKREK AVEEEKNKLE KQLEEEVKKA KALKEEQENQ RKVMETEKKK
LQDKMDEAMR KQKEAQAEME KKQKEMDELE RKRLEQEKLL EEENKKLREK LLNIEVASKQ
GTFKTKEMEV QTEKVPEEQL VSMTMVGTTK KVLNGSVEVD GMKKDGESAF MFDGIREKVP
AERLFDIGVL TKKDMDKLKK GKVSVSDLEN TEKVRSCLKG QGCVGVVLTP SREKMSVYQA
MKEKKISPSA AASLLEAQAA VGYIIDPVKN TPLSVDEAVK EEIIGPELHD RMLSAERAAT
GFKDPYTGAK ISLYEAMKKE LVDKEQAMKF LDVQLATGGI VDPINSHRVQ LPMAYKQGQF
DEDLNKKLND PSEDLKQFID PSSQEKLTYK QLLERCTKDA ETGLWILPVT EKAAQVERTF
TDSETKEVFS KSKVDVPFGK FKGKTVTIWE VINSEYFTED QRRELIRQYK TGKITVEKII
KIVITVVEDK EKNSGNEFSG LRAPVPANEL LESKVINKDL FNKLSNGKIS VKEVSEMGAV
KKALHGTPSI AGLLDELTNE KIPFYQAMKE ELISPKTAVN LLEAQAATGF MIDPVKNERV
PVDEAVKSGL VGPELHECLL SAERAVSGYR DPYTGKKVSL FEAMNKGLVK KDHGIRLLEA
QLSTGGIIDP VKSYRIPHEV ACKRGYFDED FGKILNKNTD ETKVFNDPTS QKPATYAELI
DKCVTDKDTG LPLLPLSKKA PKPKEEQQIT EAKTKEALNH TTMELEHGPF KGRKVTIWEI
IHSEYITEEQ RIEIIRQYRM GQVTIERLIK IVITMVDEKE DKTSKEPCFE GLRAPVPATS
LFESKIIDKT TFDQLQQGNI TPKEVGQTDK VRKYLQGTDR IDGITMEDSD KKLSIYQAMK
KKILQHNTGL ALLEAQAGTG YITDPVTNTK HSVDDAVKVG VVGPELHEKL LAAEKAVTGY
KDPYTGNKIS LFQAMKKELV LREHAIPLLE AQFTTGGIID PVSSHRVPND VAIQRGNFSK
QMCKSFIEPS GDVKGFTDPN TLQSATYKEL LEKCRRDPNT GLCYLPLSKV EAPAPDEKSY
EFTEEQAQTD LANTQIEIPL QRFAGKNMTV WEVMNSNLLP EEERLRLLEQ YRLGQITKER
MLIIIIEIME HRETLQAEQS MSCDVIRRRV TIEELYSARI IDLETYNLLK QEKMTIRELM
DMPSVKQFLF GTGCIAGILS DTPPKISIYQ ALKKGQIKPE VALKLLEAQA ATGFIIDPVK
DELLTVDEAV RKGLVGPELH DKLLSAERAV TGYKDPYSGK VISLFQAMKK DLIPEDYALR
LLEAQLATGG LMDPEYYFRL PTDVAMQRGY INKETLDRIS EPNADVRGFI DPTTDEKQSY
AQLLKRCRVD KDSGLRLLSL ADRKLLFKGL RKQITVEELL RSQIINQKTY NDLTEGTISV
EEVSRDVKKF LEGTSCIAGV FVESSKERLS IYQAMKKNMI RPGTAFELLE AQAATGYVID
PIKHLKLNVA DAVKMGVVGP EFKEKLLSAE RAVTGYKDPY SGKIISLFQA MKKGFILKDH
GIRLLEAQIA TGGIIDPEES HRLPVEAAYE RGLFDEEMNE ILTDPSDDTK GFFDPNTEEN
LTYLQLTERC LTDPETGLRL LLLKEKKRER KTSSKSSVRK RRVVIVDPES GKEMSVYEAY
QKGLIDQQTY LELSEQECEW EEITTTSHDG SVKSLIIDRR SGRQYDIDDA ISRALIDKSA
LDQYRAGTLS ITEFADMLSG NMSGSRSRSS SFGSSSSYPM SPIPSIKTPA TTWNDPTEET
GPIAGILDTD TLEKVSVTEA IHRNLVDNIT GQRLLESQAC TGGIIDPNTG ERFMIADAMN
KGLVDKIMVD RITLAQKAYI GFEDPRTKTK MSAAQALKKG WLYYEAGQRF LEVQYLTGGL
IEPEATGRVS IDEAVRKGTL DARTAQKLRD VSAYSKYLTC PKTKLKISYK DALERSMTEE
GTGLRLLEAS SQSSKGLYSP YSISGSGSAT GSRSGSRTGS RSGSRRGSFD ATGSSFTSTF
SSSSYGSPSY SRRY
//
