ID A0A3B3CIY3_ORYME Unreviewed; 959 AA.
AC A0A3B3CIY3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Huntingtin interacting protein 1 related {ECO:0000313|Ensembl:ENSOMEP00000017802.1};
GN Name=HIP1R {ECO:0000313|Ensembl:ENSOMEP00000017802.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000017802.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000017802.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SLA2 family.
CC {ECO:0000256|ARBA:ARBA00010135}.
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DR AlphaFoldDB; A0A3B3CIY3; -.
DR Ensembl; ENSOMET00000026614.1; ENSOMEP00000017802.1; ENSOMEG00000021109.1.
DR GeneTree; ENSGT00940000153594; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR Gene3D; 1.20.5.1700; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 6.10.250.920; -; 1.
DR Gene3D; 1.20.1410.10; I/LWEQ domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR032422; HIP1_clath-bd.
DR InterPro; IPR035964; I/LWEQ_dom_sf.
DR InterPro; IPR002558; ILWEQ_dom.
DR InterPro; IPR030224; Sla2_fam.
DR PANTHER; PTHR10407; HUNTINGTIN INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR10407:SF10; HUNTINGTIN-INTERACTING PROTEIN 1-RELATED PROTEIN; 1.
DR Pfam; PF07651; ANTH; 2.
DR Pfam; PF16515; HIP1_clath_bdg; 1.
DR Pfam; PF01608; I_LWEQ; 1.
DR SMART; SM00307; ILWEQ; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF109885; I/LWEQ domain; 1.
DR PROSITE; PS50945; I_LWEQ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT DOMAIN 690..929
FT /note="I/LWEQ"
FT /evidence="ECO:0000259|PROSITE:PS50945"
FT COILED 397..520
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 888..924
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 959 AA; 107529 MW; AEC6EA844F50C683 CRC64;
LQSLSKIVAT NESPPKEKYV RNIILGTHKE TGATTFWSYA VNLPVSSNSM VSWKFCYLLH
KVLRDGHRNV STGPHKVIPG NMEATDDTLE REAGTDMTKL DANGAKSTTP AGQCRLTPLI
PLILDSSFLY HFSVRLLFKL HSRSSLLGHK SLKFAVWFTA VFVCSLTHFY KRAREMEFFK
SVIQIPDLPD EPPNFLRAAA LAEYKKPVVV MPGEDYQEEE VETHPEFREI PQMPQMPQVR
LDMNKTKYYL SSRANSWSLW QQYYLLSQMG APEVPAEPVE TETDGWRREM EALKPEIQII
KDEAQKSVIE LTTQLSHMEA ELDAQRTHNQ VAMIENEHLR MEVEALRSVT SSSRFCPPAG
RAQAAELRFS QLKERHAELV TSHADLMKKN AEAVRMLSSS KQEQDDLLRT KTNLEKELDN
LRWDKQTKQK QEIDRLRREL DSTRAELTRA NSALQSKEMS GTQLNSTLAG LQAEKEVLLR
SVREQEAELN SLRQQAHLQH SSLEQERQRS SMELGSLQAQ LQQQACRETE LAQKLQNEQF
ALLQCAVVEA EGIILDAVAK LDDPIHVRCT SSPDYLVNRA EVTLGSIDKL QQSHLVYLGN
RSDASGLLRA VTQFSHLAAD TIVNGAATSH SAPVDHADSL SDSCRDCANQ CLQFLKDLKF
QPTLPQANAS AIRYSVQRIL AMGQDLRPKG QDVLKEELGT MVDKEMVATS TAIEDAVLRM
DEILSQARRD TTGLKLEVNQ SLMCFFSLQA VHILVTAATD LQKDIVEGGR GAASTTEFYA
KNSRWTEGLI SASKAVGWGA TQLLDSADRV VSEKGTYEEL IACSHEIAGS TAQLVAASKV
KADRSNKKLN TLQQASRHVN DMAAVVVTST KHGQKQISDH GLMDFSGMSL IKLKKEEMEA
QVKVLQLENQ LEQERIRLGE LRKRHYDLGP SAMGHRRFLS GINQHEARPA APTTRTRSV
//
