ID A0A3B3CLT9_ORYME Unreviewed; 925 AA.
AC A0A3B3CLT9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Amyloid-beta A4 precursor protein-binding family A member 2-like {ECO:0000313|Ensembl:ENSOMEP00000018531.1};
GN Name=APBA2 {ECO:0000313|Ensembl:ENSOMEP00000018531.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000018531.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000018531.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3CLT9; -.
DR Ensembl; ENSOMET00000027567.1; ENSOMEP00000018531.1; ENSOMEG00000020285.1.
DR GeneTree; ENSGT00940000158943; -.
DR Proteomes; UP000261560; Unplaced.
DR CDD; cd00992; PDZ_signaling; 2.
DR CDD; cd01208; PTB_X11; 1.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR12345:SF12; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY A MEMBER 2; 1.
DR PANTHER; PTHR12345; SYNTENIN RELATED; 1.
DR Pfam; PF00595; PDZ; 2.
DR Pfam; PF00640; PID; 1.
DR SMART; SM00228; PDZ; 2.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50106; PDZ; 2.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 556..731
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 744..829
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 835..911
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..98
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..154
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..239
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 298..316
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..364
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..499
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 103655 MW; CB4E270DCD0A76FC CRC64;
MAQRKRPGSC GGSSMPTQGP ASCPTPRPVE SCDLKALPPR QRPLRYHKES CDPKAPSHSC
KAQYSSLTPH EVDHGSPQKD AEVEGKQYSN KEADIEIENQ HPATPPLPEH NHDDQDEADF
HGGADSLDDD SSSDYINNTS DDEEDYDDGL AEEDEGVTYY IRYCPEDDSY LEGMDCSSQG
ECNHSHSQGG CAMQKGESHP DECQEAVEEW GEEEQEEADG EVREEEEWAE DEEGEEDVRG
EWREEQGEAR EEWRDRDEEV QEEWREESQV RHEQWVGRER QRVEEWCEEE GEVRCEVVEQ
DPDEQIYNGR PEPILDHHHH HRYHHQPDVP DALHTCRGDR EEEQEAESEE YNPNEEEEEE
DGEEEERHGR AYTGDYYVPE DNGNSVMVSS YSGRKVLVVE GETGEEAEED IDQIVAEVKM
SMSMGSLSSG TDQSPEELAQ DPAPTVYSHS KPEAAPYPPP HHRHDSRPKS LNLPSMHHNN
PDLQRGVKAH PRSPEDRQRW SQEQGGNGAE QPRKQQRSDL NVPLENNNVP EPTKKVASFP
SFVDVPGPCE PEDLIDGIIF AANYLGSTQL LSERNPSKNI RMMQAQEAVS RVKNADGDTQ
TLTEVDLFIS TQRIKVLNAD TQETMMDNAL RTISYIADIG NIVVLMARRR MPRTASQDCI
ETTPGAPEAK KQYKMICHVF ESEDAQLIAQ SIGQAFSVAY QEFLRANGIN PEDLSQKEYS
DIINTQEMYN DDLIHFSNSE NCKELQLEKS KGEILGVVIV ESGWGSILPT VILANMMNGG
PAARSGKLSI GDQIMSINNT SLVGLPLATC QGIIKGLKNQ VQVKMNIVSC PPVTTVLIKR
PDLKYQLGFS VQNGIICSLM RGGIAERGGV RVGHRIIEIN GQSVVATAHE KIVQALSNSV
GEIHMKTMPA AMFRLLTGQE TPIYI
//
