ID A0A3B3CN76_ORYME Unreviewed; 447 AA.
AC A0A3B3CN76;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Nucleoporin 50 {ECO:0000313|Ensembl:ENSOMEP00000019333.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000019333.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000019333.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B3CN76; -.
DR Ensembl; ENSOMET00000028547.1; ENSOMEP00000019333.1; ENSOMEG00000021157.1.
DR GeneTree; ENSGT00440000035348; -.
DR OMA; DRGIFKT; -.
DR OrthoDB; 4273059at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd13170; RanBD_NUP50; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR015007; NUP2/50/61.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR045255; RanBP1-like.
DR PANTHER; PTHR23138:SF141; NUCLEAR PORE COMPLEX PROTEIN NUP50; 1.
DR PANTHER; PTHR23138; RAN BINDING PROTEIN; 1.
DR Pfam; PF08911; NUP50; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR SMART; SM00160; RanBD; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 4: Predicted;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00023132};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022816}.
FT DOMAIN 306..447
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..91
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 46907 MW; C293A92E34A78A2A CRC64;
MAKRIADKEL TDRNWDQEEE GEEAGTFCLA SEDVLKSRPI KKAKRRNVGA EAEGGGAFKG
FKGFAFSASA ASAASTPPTG PSFGTSEGFK GFGSLTNGGA PAFGGFSPVP ASSAAAGVNG
GSASFSKPPA DSSTNQANGS APSSAPAALS CSRSREYSRQ LAALNRSVRD WISKHVDDNP
LCDLNPIFRD YERHLASIER KFGGGRDNPE EKAAPAEPAP PPSSGSAAAP PSGALFSFSR
NSSESNSDPA PAAVTFNFGQ KVDSSVLNPL GSKPLGTTFS FTPSPSQTPL FGAASSLAPL
PLGGTKTEEA PPTDENGDAE SEEPPKPEVK EVKEDDAFYS KKCKLFYKKD SEFKEKGVGT
LHLKRTADGK TQMIIRADTN LGNILLNIMV HASMPCSRVG KNNVMVVSVP NPPVDDKNPS
GPVPLLIRVK TAEDADELQQ TLEERKA
//
