ID   A0A3B3CNS3_ORYME        Unreviewed;       241 AA.
AC   A0A3B3CNS3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Adenosine 5'-monophosphoramidase HINT3 {ECO:0000256|ARBA:ARBA00039802};
DE   AltName: Full=Histidine triad nucleotide-binding protein 3 {ECO:0000256|ARBA:ARBA00042361};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000019226.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000019226.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine 5'-phosphoramidate + H2O = AMP + NH4(+);
CC         Xref=Rhea:RHEA:67916, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:57890, ChEBI:CHEBI:456215;
CC         Evidence={ECO:0000256|ARBA:ARBA00024472};
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DR   AlphaFoldDB; A0A3B3CNS3; -.
DR   STRING; 30732.ENSOMEP00000019226; -.
DR   PaxDb; 30732-ENSOMEP00000019226; -.
DR   Ensembl; ENSOMET00000035583.1; ENSOMEP00000019226.1; ENSOMEG00000021063.1.
DR   GeneTree; ENSGT00510000047616; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR12486:SF5; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3; 1.
DR   PANTHER; PTHR12486; APRATAXIN-RELATED; 1.
DR   Pfam; PF11969; DcpS_C; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          14..120
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   MOTIF           104..108
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00464"
SQ   SEQUENCE   241 AA;  27782 MW;  50BB5B2D07BA7BE0 CRC64;
     MASDESEKYD ESCIFCLIAK NQDEETEVIK QNEELVCFRD ICPAAPHHYL VIPREHIHSC
     CSLKHVLLLR MTSMGRAVLK EQGITNMEEV RLGFHQPPFI SVGHLHLHVL APVRQISTCF
     EYKFTPETDS FVTVSTDGLI YYVLVFSIRH IVKTVTSYFL IILERTLVLY TKLLTSLVIC
     FLPLLHNKSL SIAGGIFKEE TTENCSTYWD QVYFWKMFRT TLKRNVSLKQ NCVFVSSECT
     A
//