ID A0A3B3CR05_ORYME Unreviewed; 1702 AA.
AC A0A3B3CR05;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Neurexin 3b {ECO:0000313|Ensembl:ENSOMEP00000019519.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000019519.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000019519.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR STRING; 30732.ENSOMEP00000019519; -.
DR PaxDb; 30732-ENSOMEP00000019519; -.
DR Ensembl; ENSOMET00000028767.1; ENSOMEP00000019519.1; ENSOMEG00000021431.1.
DR GeneTree; ENSGT00940000167343; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR003585; Neurexin-like.
DR PANTHER; PTHR15036:SF48; NEUREXIN-3B; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00294; 4.1m; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00282; LamG; 6.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..1702
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017184013"
FT TRANSMEM 1625..1645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..203
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 194..231
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 257..439
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 446..638
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 642..679
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 684..856
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 870..1045
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1057..1094
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1098..1298
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 1329..1372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1428..1474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1511..1564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1666..1702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1329..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1441..1455
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1666..1688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1702 AA; 186845 MW; 58198E195266D13A CRC64;
MNPNSLFRRV VMLLSTMLGL SASLEFPGSK GQWARYQRWD ASSTSDLTFQ FKTSASEGLL
LYFDDGGYCD FLLLTLSEGK LQLHVSIDCA ETTITSAKMV NDSRWHFAAI NRENLRTGLA
VDGQIKTGEV RPQRHFMKIV SDLFLGGLPE DIRISAITLP SVCELPAFRG VISDLSYGSK
LPTLINSQKV RLEMIGLCTE NPCENGGICS LADGETYCDC SRTGYVGRYC TEAVPRKPGL
AHLKAEQGRN KVREENVATF RGSEYFCYDL SQNPIQSSSD EITLSFKTWQ RNGLLLHTGK
SADYVNLALK DGAVSLVINL GSGAFEAIVE PVNGKFNDNS WHDIKVTRNL RQVTISVDGI
LTTTGYTQED YTMLGSDDFF YVGGSPSTAD LPGSPVSNNF MGCLREVVYK NNDIRLELSR
LARIDDPKMK LQGDIVFKCE NVPTLDPINF ETPDSFLALP KWNTKRVGSI SFDFRTTEPN
GLILFTQGRP QDRRDAKGQK NNKVDFFAVE LLDGALFLLL DMGSGTIKVK ATQTKVNDEA
WHHVDIQRDG RSGIISVNSH RTPFTASGEN EILDLEGDLY LGGLPYNRAG LVLPTELWTA
MLNYGYVGCI RDLFIDGRSK NIRQIAQSQN ITDIKFSCSK VSGKHCDSSP CKNNGACREG
WNRFVCDCTG TGFWDSTCER ESSILSFDGT MYMKVVMPNV MHTEAEDVSL RFMSQRAFGL
LMAASSRESA DTLRLELDGG RVKLTVNLDC VRINCNTSKG PEVLYAGEKL NDNEWHSVRV
VRRGKNFKLI VDEDMAEGQM AGDHTRLEFN NVETGILTEK RFVSSAPSPF IGHLQSLKFN
GMQYIDMCKN GDIDFCELNA RFGMRFIIAD PVTFKTKASY LGLATLQAYT TMHLFFQFKT
TSPDGFILFN SGDGNDFIAV ELVKGFIHYV FDLGNGPSLL KGNSDSPLND NQWHNVVITR
DASNTHTLKV DSKSVNQNVN GAKNLDLKGD LFIGGLGPNM YQNLPKLVVS REGFQGCLAT
VDLNGRLPDL ISDALFRSGQ IERGCEVAFT KADLQGPSTT CQEDSCANMG VCIQQWENFT
CDCSMTSYTG TYCNDPGTTY IFGKGGGLIT YTWPNNERPS TRADRLAVGF STTITDGILV
RIDSAPRLAD YIMLHIEQGK VGVTFNIGTV DISVKETSTL VNDGKYHLVR FTRNGGNATL
QVDNWPINEH FPSGNSDFER FQMANKKIPF KYTRPVEDWL QEKGRQLTIF NTQATISIGG
NDRKRPYQGQ LSGLYYNGLK VLNMAAEGHP NIKVTGSVRL VGDVPPSRGA TRTTTSVPPE
MSTTFIETTT TLSTTTTRKQ RSPPTIQTTD DIVSSAECSS DDEDLEECDS GHTGGELVIP
VLVEDPIDIP SVSTRSPFIP LPPTLRPVLT IIETTKESLA MATEAGVPCL SDRGSDDCDG
GDGGDDGDDG DDDDGMVISG FGSGEAFDSS LPPTDDEDFY TTFSLVTDKI LTTSAYEGGY
KALAPKWEAK DLRPSKASES GRTTPTLAQP NIRGTPPAAV PSDTPPKLPA GKMNNREVKP
PQPDMVLVPL PTSFDMDGTK PRGPFITSPM LRTVPAPLPT VPGVVRRVPS GASEVIRESS
STTGMVVGIV SAAALCILIL LYAMYKYRNR DEGSYQVDET RNYISNSAQT NGAVVKDKAP
SSNAKGNASS KRPKDKDKEY YV
//
