ID A0A3B3CTU3_ORYME Unreviewed; 622 AA.
AC A0A3B3CTU3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator-like protein 2 {ECO:0000313|Ensembl:ENSOMEP00000021267.1};
GN Name=BMAL2 {ECO:0000313|Ensembl:ENSOMEP00000021267.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000021267.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000021267.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3CTU3; -.
DR STRING; 30732.ENSOMEP00000021267; -.
DR PaxDb; 30732-ENSOMEP00000021267; -.
DR Ensembl; ENSOMET00000030894.1; ENSOMEP00000021267.1; ENSOMEG00000023136.1.
DR GeneTree; ENSGT00940000160423; -.
DR OMA; ETYRYCT; -.
DR OrthoDB; 2872674at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF48; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
FT DOMAIN 77..130
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 157..223
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 350..399
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 1..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 501..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..466
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 622 AA; 68658 MW; 6DE31AF52E872B72 CRC64;
MSADGSDPAA DKPADCGEEE EGSCTAGSSM PAVELPRKRK GDVEERSNTH AQHGLDCQMD
DDVSRSEGED QQVKMKCFRE PHRQIEKRRR DKMNNLIDEL SAMIPACQPM ARKLDKLTVL
RKAVQYLKSL KAGTSGAFTD TTCKPSILPH DDLWHLLLRT ANGFLLVVRC DRAKILFISE
SVSKILNFSQ LELTGQSLFD FIHPKDINKV KEQLSSSELL PRQRLIDAST GVQVPVEAPV
RTHHMSTGAR RSFFCRMKHS RVAGKHEDKH ALPNASKKKD GYRYCTLHCT GYMRSWPSSQ
LDPEGDAVDK DTSSMSCLVT MCRLHSHVSY QVPKDVKVRA TEFVTRCAID GKFTFVDQQA
TTVIGYLPQE VLGTSCYEYF HQDDLQHLAA KHRQVLRSKE KIETQSYKFK TKYGSYISLQ
SQWFTFTNPW TKEVEFIVSL NRVVPGPGHT KDEEAGASKA LHEDTKPLSD IPGLSDSVGT
MIYAGSIGTQ IANELIDTYR ANSSPSSGSS SPFGPALEKC PQASKSASEP SETKALPVQA
RRDEEAGSSS QSQSGSRTDE SVSGAASEST GETSQLDLEI MGVSGLSSFS SDEAAMAVIM
SLLETDVNMG QSGDFDDLHW PF
//
