ID A0A3B3CV66_ORYME Unreviewed; 1253 AA.
AC A0A3B3CV66;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rho GTPase-activating protein 30-like {ECO:0000313|Ensembl:ENSOMEP00000021718.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000021718.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000021718.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3CV66; -.
DR STRING; 30732.ENSOMEP00000021718; -.
DR PaxDb; 30732-ENSOMEP00000021718; -.
DR Ensembl; ENSOMET00000031465.1; ENSOMEP00000021718.1; ENSOMEG00000023651.1.
DR GeneTree; ENSGT00940000165396; -.
DR OMA; FLDQMDC; -.
DR OrthoDB; 4248575at2759; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04384; RhoGAP_CdGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15729; CDC42 GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR15729:SF12; RHO GTPASE-ACTIVATING PROTEIN 30; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054}.
FT DOMAIN 17..212
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 295..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 980..1130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1150..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..558
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..582
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..737
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..816
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..844
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..887
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..932
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 988..1036
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1039..1055
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1060..1089
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1161..1214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1253 AA; 138511 MW; D2A016DABA464A5F CRC64;
MRRVRRRGGN KEKVFGCDLL EHLSTSCHEI PLVLRCCSEF VEEHGVVDGI YRLSGVSSNI
QKLRGEFESD GSPDLNKDVY LQDIHCVSSL CKAYFRELPN PLLTYQLYDK FAEAVAIQLE
EERLVKIRDV LTELPAPHYR TLEYLMRHLV RMASFSSETN MHARNLAIVW APNLLRSKDI
EASGFNGTAA FMEVRVQSIV VEFILTHVPQ LFPGEGASGE RRKSLPSPSA MYGQDVLFQR
ASHMQPAVNF GNISPGDGPL PIRPYHAIIE GTDKRKGSLK GRKWMSIFNI GGRFQETRKK
HKSSTKEKEK VVLRPARSMD SLSSPSYPNE GSRRSGQRPP SNSMTPIVPP SPQSGSKLAP
AAGGMGGSEY AVTYRRGTGL VSGGAGTMGT YTAIDPEGLG LPSSEVVQAR SPGLSSKVGR
RAAMHITGPT TVTVPLHITS NLALGVLQAA GSDRLIHRGR DKDSGDKAEG KEEGDKLESK
EPRRTKRKSE ESREAEEVQE SKGMRSQDKG SVSEEQGCGV KIGGDKEVTN LTKQEPTMAD
QGASRKQPTK SVNSNTSDSV GREDHESGSE YIDMKGAEEL EDGSDNDGVF GASDVLNSTE
EEGYDIELSG YVQDNFDFLD HMDCSVLDHM DSSAAYQVNE FSVEPPGHSY DEYEMMEQAQ
SSHHPTVAQE AATPVPDVHP HSGAELKPHR PLSLDLHSRH TKSLSLPYIT SPIHGQQESS
SEEEVSAEED SHDEDYSSGE DESMFVQSLP ADFLLSTLSG LDLGAKESKL SQSDQSQVQE
LPSSEEEHCP QLPTNKETIT SDDEQEDGDD EEDKDGSEKR EDQRMEVENK LESKEAEERP
SVMREAQSQK PQTLETLTPC CLEFPSSENE DESNSAAEMK TEDNDDISPV DSLSEVPLCT
PQPETVSPEE FIETLESPKD PSEGDAPKSD DECQQSVPEM TETTKKPCQD LIFNEQESGV
CRENHDLWID LEDVVCEVIE ERENEQSEAE GTEVKKEEEE EDKQTGSGSE EKTVKADEAE
TNKSEVREES VGEAVKTPEE KFTNSSAGKA ETANQETCDV TEEDGDHKIE GVVQGTDREK
KELDGELSRA QQSADKSPPM PKVRPKESND SGTGEIGIRG VGRKLVVSKQ PKVYQVKAVP
VVPPKPQHCK ITALTLRQQQ QKERLEADKG RDGPPRVQPE PDREARDGAE ESLDRQERQI
ILRERRRDGP ERDSSSRNSP LSLCFDEAVA IATMRREKER AREGEVDVDR LGK
//
