ID A0A3B3D0J3_ORYME Unreviewed; 786 AA.
AC A0A3B3D0J3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000023642.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000023642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B3D0J3; -.
DR STRING; 30732.ENSOMEP00000023642; -.
DR PaxDb; 30732-ENSOMEP00000023642; -.
DR Ensembl; ENSOMET00000011705.1; ENSOMEP00000023642.1; ENSOMEG00000003846.1.
DR GeneTree; ENSGT00940000164725; -.
DR OMA; RFRRERM; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR032455; Cadherin_C.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR PANTHER; PTHR24028:SF288; PROTOCADHERIN ALPHA-C2-LIKE-RELATED; 1.
DR Pfam; PF00028; Cadherin; 5.
DR Pfam; PF08266; Cadherin_2; 1.
DR Pfam; PF16492; Cadherin_C_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 6.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 679..702
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..120
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 121..229
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 230..337
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 338..442
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 443..552
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 567..670
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 786 AA; 87493 MW; 05CC3194B5B4CC5E CRC64;
VFLVLPIVQI VSTSVTPYSI PEEMKEGSVV ANLASDLRLD VKTLNERKMR LDIVANKKYL
DVNKETGELY IVEKIDRENI CPSKSSASCY LRLEVTLENP LRIFNIEIEI LDMNDNAPQF
RRDAIHLDIS ESTPKGDRFS LSNAVDPDVG SNSVKTYHLS ESEYFNIEVQ TGRDGSKFAD
LILKKTLDRE QQAVHHLTLT AVDGGKPARS GTASVIVHVL DTNDNTPTFD KSIYNVKIME
NSPIGSLVLH LNATDLDEGS NSDITYSYSL YTSEKTQETF HLNPTSGEIT VRGMLNYEDF
NIYDMEVIAT DKGANSLSGQ CTIKILVEDM NDNHPELSIK SFQSPVSEDI KLDTVIAVVS
VSDKDSGENG IVDLHIPDNM PFKLRESSDN YYELVVSEAL DREKVPEYDI TFTVTDRGSP
PLSDNETMTL ELLDVNDNVP QFPKSFYTIR VMENNAPGAL LESLSAFDPD LHENQYLVYV
IIEKEIANTS MSMLFSINPE DGKLYALKTF DYEIEKEFLF HIEARDSGSP PLSSNVSVHI
IIVDQNDNAP VIVSPWRAHG SVVEEKIPRS TDKGSLVAKV IALDTDSVHN SRITYQFLQV
TDATLFSLDQ YNGEIRTMRM FSYRDPRHQR LVVVAKDNGE PALSATVTIK LSTEETAVKA
YSDMTEVPLE YDIFSDLNLY LVIGLGSVSF LLLITILVTI VLKCQKAKPS KAAPPSRNSV
ISERNSTIAD STLVSNDAYW YSLFLAETRK GKLVVRQPVP KGSRYIVSSI PRGTGLTDTS
DSAAST
//
