ID A0A3B3D3Y1_ORYME Unreviewed; 555 AA.
AC A0A3B3D3Y1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Lysine (K)-specific demethylase 7Ab {ECO:0000313|Ensembl:ENSOMEP00000024135.1};
GN Name=KDM7A {ECO:0000313|Ensembl:ENSOMEP00000024135.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000024135.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000024135.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|ARBA:ARBA00001954};
CC -!- SIMILARITY: Belongs to the JHDM1 histone demethylase family. JHDM1D
CC subfamily. {ECO:0000256|ARBA:ARBA00006942}.
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DR AlphaFoldDB; A0A3B3D3Y1; -.
DR STRING; 30732.ENSOMEP00000024135; -.
DR PaxDb; 30732-ENSOMEP00000024135; -.
DR Ensembl; ENSOMET00000010437.1; ENSOMEP00000024135.1; ENSOMEG00000004584.1.
DR GeneTree; ENSGT00940000158039; -.
DR OMA; PWEEDIT; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.1360; -; 1.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR041070; JHD.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR PANTHER; PTHR23123:SF15; LYSINE-SPECIFIC DEMETHYLASE 7A; 1.
DR PANTHER; PTHR23123; PHD/F-BOX CONTAINING PROTEIN; 1.
DR Pfam; PF17811; JHD; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 5..56
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 198..354
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
SQ SEQUENCE 555 AA; 63447 MW; 1D49D681D5382BE8 CRC64;
MAAAPLYCVC RQPYDVSRFM IECDICKDWF HGSCVQVEEH HAVDIDVYHC PNCDVKHGPS
LMKKRNNWHR HDYTEPDDGT KPVQAGTSKF VKELQNRTFP SAEEILIRMK GEQVTARFLE
RHGFNYPIAV TEMEGLGLKL PPSTFSVRDV EQYVGGDKVI DVIDVARQAD SKMKLGTFVK
YFTNPHRPKV LNLISLEFSD TKMSELVEVP DVARKMSWVE NYWPDDSFFP KPFVQKYCLM
GVKDSYTDFH IDFGGTSVWY HVLWGEKIFY LIKPTSTNLA LYEAWSSSPN QSEVFFGDKV
EKCYKCVVSQ GTTLLIPTGW IHGVLTSQDC MAFGGNFLHN LNIGMQLRCY EMERRLKTPD
LFKFPYFEAI CWYVAKNLLE MLKELREDNC PPSTYLVDGV KALISALKTW LKREATQPTS
EVPDHIRPNH LIKELTKEIR YLEGCGAPAG TNGCPATRSA LERFCQARRA RRAARRLREQ
QQQAPKLPTN LDILEQHTRE VLKRLEVGPL EEDAAFCAKV HGKLNKVSTA SAAAAAESLE
DNHLRLMMVN GRIIR
//
