ID   A0A3B3D3Y7_ORYME        Unreviewed;       276 AA.
AC   A0A3B3D3Y7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=N-chimaerin-like {ECO:0000313|Ensembl:ENSOMEP00000024140.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000024140.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000024140.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3D3Y7; -.
DR   Ensembl; ENSOMET00000010426.1; ENSOMEP00000024140.1; ENSOMEG00000000749.1.
DR   GeneTree; ENSGT01030000234635; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0048468; P:cell development; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR046349; C1-like_sf.
DR   InterPro; IPR002219; PE/DAG-bd.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR46075; CHIMERIN FAMILY MEMBER; 1.
DR   PANTHER; PTHR46075:SF6; N-CHIMAERIN; 1.
DR   Pfam; PF00130; C1_1; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
DR   PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          57..276
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   DOMAIN          80..111
FT                   /note="Phorbol-ester/DAG-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50081"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   276 AA;  31466 MW;  719C21AF5BA6C69E CRC64;
     MPSRESYNVQ KKEKPLVEKA KQEASQEDIL ATALGMRMGP QKTSATFWQP IKILACSQLS
     SLVRRATLRD GDWTPKSEKV HNFKVHNFRG PHWCEHCARF MWGLMAQGVK CTGLKSEGLY
     RISGFSDSVE EVKTGFDKDG EKTDISVKAY EDINIITSAL KLYLRDLPVP VISYDSYPRF
     IEAAKLTEPE KKLEAFREAL ALLPLSHRET LKYLMAHLKR VTQNEKFNLM SAENLGIVFG
     PTLMRAPDQD AITALNDVRY QRQVVEVLIK NEEVLF
//