ID A0A3B3D6R2_ORYME Unreviewed; 851 AA.
AC A0A3B3D6R2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000025862.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000025862.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3B3D6R2; -.
DR STRING; 30732.ENSOMEP00000025862; -.
DR PaxDb; 30732-ENSOMEP00000025862; -.
DR Ensembl; ENSOMET00000006018.1; ENSOMEP00000025862.1; ENSOMEG00000007376.1.
DR GeneTree; ENSGT00940000163991; -.
DR OMA; RNITWAY; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR InterPro; IPR017978; GPCR_3_C.
DR InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR InterPro; IPR017979; GPCR_3_CS.
DR InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR Pfam; PF00003; 7tm_3; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF07562; NCD3G; 1.
DR PRINTS; PR00248; GPCRMGR.
DR PRINTS; PR01535; VOMERONASL2R.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..851
FT /note="G-protein coupled receptors family 3 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017267488"
FT TRANSMEM 587..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 623..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 658..681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 701..720
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 746..769
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 781..801
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 813..837
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 587..851
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|PROSITE:PS50259"
SQ SEQUENCE 851 AA; 94216 MW; F04A4C9A64336E40 CRC64;
MILVLPLCLF EMNSVFFLGG SLTGLKQRTG VDVANIDASS VRCNLRGVAR SPGFSKDGDF
IIGGVFSIHY NMYTEMYNYV TMPDPPKCTG SMNVRGLRFA RAMIFAIEEI NNSTELLPGI
NLGYQIHDSC SAVPVAVQAA FQLSNGGDNI FYKNDICSQS GMMAAFVAES GSTPSIGISQ
VIGSFDIPQV SHFATCACLS DKQQFPNFFR TIPSDAFQAE ALAKLVKHFG WTWIGTICSD
SDYGNYGMAS FLQAAKKEGI CVEFSESFYR TNQISKIQRV ADVIRRSTAT VIVAFASSGD
MKVLLGELAR KPSRSWQWIG SEAWVTDPNL LKFDFCEGAL GFGIQKAIIP GLRDFLLDLS
PSELGFNLIK WTRYKIRMGK LSQACKQHCL GRHSYFVFSP YTETSQLRVT NMVYKAVYAI
AHAIHSVVCP ERNFTTKCDK PLKKVNFTRN GYSVSFDVNG DPVAVYELVN WQKGESGVNE
LVTVGYYDAS FPINKEFHIT RNLTWMDGSK QVPKSKCTDS CPTGTHKVLQ KGKPICCYDC
IQCPEGEISN TTDSSDCFPC SIEFWPSAER DSCHPKPVEF LSIDETLAIV LAVFSVSGAC
LAILTAAVFF YHRTTPIVRA NNSELSFLLL FSLTLCFLCS LTFIGAPTEW SCMLRHSAFG
ITFVLCISCV LGKTIVVLMA FKATLPGSNV MKWFGPPQQR LTVVLFTFVQ VLICTVWLVA
RPPFPMKNFS TYKEKIILEC ALGSAIGFWA VLGYIGLLAV FCFVLAVLAR KLPDNFNEAK
FITFSMVIFC AVWLTFIPAF VSSPGKLTVA VEIFAILASS FGLIMCLFAP KCFIILCQPE
KNTKKYLMNK K
//
