ID   A0A3B3DA29_ORYME        Unreviewed;       382 AA.
AC   A0A3B3DA29;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=GDNF family receptor alpha-2-like {ECO:0000313|Ensembl:ENSOMEP00000026230.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000026230.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000026230.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GDNFR family.
CC       {ECO:0000256|ARBA:ARBA00005961}.
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DR   AlphaFoldDB; A0A3B3DA29; -.
DR   Ensembl; ENSOMET00000005087.1; ENSOMEP00000026230.1; ENSOMEG00000007993.1.
DR   GeneTree; ENSGT00940000156168; -.
DR   OMA; EWMDSIP; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR   InterPro; IPR016017; GDNF/GAS1.
DR   InterPro; IPR037193; GDNF_alpha.
DR   InterPro; IPR003438; GDNF_rcpt.
DR   PANTHER; PTHR10269:SF4; GDNF FAMILY RECEPTOR ALPHA-2; 1.
DR   PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR   Pfam; PF02351; GDNF; 3.
DR   PRINTS; PR01316; GDNFRECEPTOR.
DR   SMART; SM00907; GDNF; 3.
DR   SUPFAM; SSF110035; GDNF receptor-like; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          19..97
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          144..225
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          235..332
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
SQ   SEQUENCE   382 AA;  43187 MW;  184A6F0AEDE05D99 CRC64;
     KGTANAFILT FAQPEWVDCI QASEMCNQNP HCSSRYRVMR QCLVGKEKET MLDNNKECQA
     ALEVLLVSPL YDCRCKRGMK KELQCLQTYW TIHMGLNEGR KQMDLSPYEP IAPNRQPDEF
     GLAAISSGRT GFHCPDTEKN CNPCLVATKA CNLNGICKRQ RSTYITTCSK LDTNKGESCN
     RKRCHKALRA FLDRVPPDLS HGLLFCPCQT EGCAERRRQT IVPECSYIDK EKPNCLELRM
     TCRQDYLCRY RLADYMNNCG KTSHTMGTCP NKDNHQACLA SFVRLIGTEM TPNYVDSSSS
     NWTISPWCTC KGSGNQEEEC LNFLQHFTNN TCLSEQPLHL HTSESVSASR SLRSKIKSLS
     NRLTPPTKGP NVYTVCTFAE NS
//