ID   A0A3B3DA55_ORYME        Unreviewed;       248 AA.
AC   A0A3B3DA55;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Tropomyosin alpha-4 chain {ECO:0000256|ARBA:ARBA00039651};
DE   AltName: Full=Tropomyosin-4 {ECO:0000256|ARBA:ARBA00042053};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000026993.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000026993.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the tropomyosin family.
CC       {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR   AlphaFoldDB; A0A3B3DA55; -.
DR   Ensembl; ENSOMET00000003104.1; ENSOMEP00000026993.1; ENSOMEG00000009197.1.
DR   GeneTree; ENSGT01030000234542; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.370; -; 1.
DR   InterPro; IPR000533; Tropomyosin.
DR   InterPro; IPR014751; XRCC4-like_C.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   PANTHER; PTHR19269:SF70; TROPOMYOSIN ALPHA-4 CHAIN; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   3: Inferred from homology;
KW   Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   REGION          20..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  28603 MW;  48319F5C4A979ECF CRC64;
     MAGVNSLDAV KRKIQCLQQQ ADEAEDRAES LQKELDSERE LREKAEGDVA ALNRRIQLVE
     EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE
     EADRKYEEVA RKLVILEGDL ERAEERAEVS ESKASDLEEE LKNVTNNLKS LEAQAEKYSE
     KEDKYEEEIK VLTDKLKEAE TRAEFAERTV TKLEKTIDDL EEKLSRAKEE NVGMHQVLDQ
     TLQELNSL
//