ID A0A3B3DP07_ORYME Unreviewed; 937 AA.
AC A0A3B3DP07;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Thrombospondin type 1 domain containing 4 {ECO:0000313|Ensembl:ENSOMEP00000031868.1};
GN Name=THSD4 {ECO:0000313|Ensembl:ENSOMEP00000031868.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000031868.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000031868.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3DP07; -.
DR Ensembl; ENSOMET00000023526.1; ENSOMEP00000031868.1; ENSOMEG00000017012.1.
DR GeneTree; ENSGT00940000156594; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR010294; ADAMTS_spacer1.
DR InterPro; IPR010909; PLAC.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF16; THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF05986; ADAMTS_spacer1; 1.
DR Pfam; PF08686; PLAC; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 6.
DR Pfam; PF00090; TSP_1; 1.
DR SMART; SM00209; TSP1; 7.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 7.
DR PROSITE; PS50900; PLAC; 1.
DR PROSITE; PS50092; TSP1; 6.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 890..927
FT /note="PLAC"
FT /evidence="ECO:0000259|PROSITE:PS50900"
FT REGION 99..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 937 AA; 104504 MW; C071E5FB05DAFCF0 CRC64;
KRKKFKDQSL DEGFLSVFGS PIVWPCPTSM IRMLCFLKVP QRAESGGPPG SWGAWGPWSS
CSRTCGNGVQ EQSRACLPVY MQRSSVQLQH PGRIISALRP SLHSDGGRAL NSSSMDLRRG
KQTRPGERSR STSILPGKYG YGRGLYVPLQ TDAGRRSESP NLHKQRRSAA ATSHHPSATG
RSSFRSTNPN NLHHFRRPAH SNAHLRHNQV WAPLYQPSSS DTGRVQPEVN PRSQERPYNP
LPTSSCSGEH AHYRICNSNA CPPSSRHIRA LQCSSYNKQP FMGRLYEWEP FNEVQEEQLC
ELHCRAVGFR FYVRHSEKVI DGTPCGPNDA SLCVGGTCTS LGCDGYLGSG KVMDKCNICG
GDNSTCRLVS ELFKHSFSKI GYHKIAEIPE GATKINVTEM VKSRNYLALR SRSGRSIVNG
NWAIDRPGRY EGGGTIFTYR RPNEISSTAG ESLLAEGPTN EILDIFIIFQ QPNPGVHYEY
ILPSQKTTGP QKPNHRPDGK FCLEKVTFRK LNRGRSPSRL PDNQVPAVQP PRRGREYNWK
QTGATECSIS CGKGKPQYSI FHCVNRLNHV QVSDSLCDSS SRPSPQEEAC NLQPCPAFWD
IGEWSECSKT CGLGMQHRQV LCRQVYANRT LNVHTSHCRH LERPETASSC QLKICSEWQI
RTEWTSCSMP CGLGQRSREV RCVSNVGDFV PDEECNMNLR PIDMENCDMG ACAKSWFYTE
WGNKCSAECG MGVRTRGVLC LKNQISSLPL EGCGSERPAD SQVCNNGPCE NRIEWFTGPW
SQCSAECGAG SQQRAVVCLM KSEDGVSVMP PYECSSLNRP LGQQSCNLKA CGAKWYHTDW
SACSKTCEGG FRVREVRCLS DDVQSSEGCD ERLKPAETES CNPEPCLPQI DENCRDKHFN
CNVVGQARLC VYKYYKETCC ASCIRAAHKQ MIHRGRS
//
