ID A0A3B3DTW1_ORYME Unreviewed; 214 AA.
AC A0A3B3DTW1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Histone deacetylase 3 {ECO:0000256|ARBA:ARBA00040349};
DE EC=3.5.1.98 {ECO:0000256|ARBA:ARBA00012111};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000032805.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000032805.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the histone deacetylase family. HD type 1
CC subfamily. {ECO:0000256|ARBA:ARBA00006457}.
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DR AlphaFoldDB; A0A3B3DTW1; -.
DR Ensembl; ENSOMET00000025328.1; ENSOMEP00000032805.1; ENSOMEG00000018452.1.
DR GeneTree; ENSGT00940000165542; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR003084; His_deacetylse_1.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF25; HISTONE DEACETYLASE 3; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR PRINTS; PR01271; HISDACETLASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 12..193
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 214 AA; 24477 MW; A6BC2250DD482867 CRC64;
AVKSSSCINM WRPHRLSLTH SLVLHYGLYK KMMVFKPYKA SQHDMCRFHS EDYIDFLQKV
SPNNMQGFTK SLNTFNVGDD CPVFPGLFEF CSRYTGASLQ GATQLNHKIC DIAINWAGGL
HHAKKFEASG FCYVNDIVIS ILELLKYHPR VLYIDIDIHH GDGVQEAFYL TDRVMTVSFH
KYGNYFFPGT GESCSRLVLA PSWICEDSRL LSCR
//
