ID   A0A3B3E2H7_ORYME        Unreviewed;       568 AA.
AC   A0A3B3E2H7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=FERM domain containing 3 {ECO:0000313|Ensembl:ENSOMEP00000035954.1};
GN   Name=FRMD3 {ECO:0000313|Ensembl:ENSOMEP00000035954.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000035954.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000035954.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3E2H7; -.
DR   Ensembl; ENSOMET00000031288.1; ENSOMEP00000035954.1; ENSOMEG00000023490.1.
DR   GeneTree; ENSGT00940000158577; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd17102; FERM_F1_FRMD3; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR000798; Ez/rad/moesin-like.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR   PANTHER; PTHR23280:SF8; FERM DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        494..521
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          19..299
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
SQ   SEQUENCE   568 AA;  65232 MW;  8EFE6FCE1E151251 CRC64;
     MMKMLRFRSP SIRSLDQEIP CTIRLLDDSE LSCSIQRDTK GQFLLDHVCN HYNLLEKDYF
     GIRYVDPEKQ RHWLEPNKPV VRQMKSHQPY MMCFRVKFYP HEPMKIKEEL TRYLLYLQLK
     RDIYHGRLLC PFAEAAYLGA CIVQAELGDY DAEEHPSDYI RDFKLFPKQS LKLERKIMEI
     HKNELRGQSA ALAELNMLQR AHSLETYGVD PHPCKDFTGA TAFLGFTATG FVVFQGNKRI
     HLLKWMDVSK LKFEGKTFYV IGIQKEKKLV LTFHTSTPAA CKHLWKCGVE NQAFYKCAKS
     SQIKTVSSSN IFFKGSRFRY SGRVAKEVIE ASSKIQREAP EVRRAQFGQS RSFNSLSHKN
     LIMNMEPLVP ALPSTNEYEE TAADSGRMIL LLMHTAGSVS CHPDVTVTGV PCASMLPSPV
     DDSQGGVDLL FSPIQSPARL LRELHADPDI QAQLEAERAR DRAYERTRLA ARSPMSGVLT
     NSLRLLSSNE RVNACVLSVV RFISVVVGVL LITVPALLLL LESDIDWSFL HEIRQTPEFE
     QFHYEYYCPL RRWILCRISM AMENLWSD
//