ID A0A3B3H5U1_ORYLA Unreviewed; 652 AA.
AC A0A3B3H5U1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000027242.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000027242.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027242.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000027242.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027242.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3H5U1; -.
DR Ensembl; ENSORLT00000042338.1; ENSORLP00000027242.1; ENSORLG00000025570.1.
DR GeneTree; ENSGT01100000263510; -.
DR InParanoid; A0A3B3H5U1; -.
DR Proteomes; UP000001038; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01650; RT_nLTR_like; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR36688; ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR36688:SF1; ENDO_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 618..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 321..589
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT COILED 152..179
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 652 AA; 76638 MW; E5A77D37E262D726 CRC64;
MYGNCLCPII NKPTRITTES ATLLDNIFTN RTDKEILGGL LFCDITDHLP VFAVLKNVSS
KKMYTQTQGK WIRCCSSDNI DSFRRALCNQ TWNEIYASTN VNEAYDAFLH RYIELYNLNC
PKIKISHKKN NEKPWITKGI EKACKKKNAL YRQFVKEKSK EAENTYKNYK NKLVNIIRNS
KKQYYHKLIE QHKLHMQETW KIINKLTKKN NKKQEYPSYF KKNDIQIRNP MLIANELNEY
FANVGNKLAM EIKEPIKKLK ELSIQSNKFS MFLSEVSSNE ILEIVRTFQN KRSKDWNDID
MSLIKNTIEF IVEPLTHIFN MSFREGIFPN NMKIAKIIPI FKNGDRHIFT NYRPISLLSQ
FSKILEKPFV KRMNNFIGKF NLLHEDQYGF RARRSTSMAI MHLVDHISSS IEKKKFTVGV
FVDLQKAFDT LNHTMLLSRL QKYGFRGIAY SWLESYLINR CQYVYFNNEK SDMCPVTCGV
PQGSLLGPIL FILYINDLCK VSDLLNCVLY ADDTTLYLSG DNLEKLLSDI TKELSIIKQW
FDSNKLSLNQ NKTKYIILGY RKRENIFELK IEDVVLERVN EIKFLGVILN HTLSWKPHIT
YILSKLSKSL AILHKVKYFL NTVTLYILYC SFMIPYLTYC LEIWGHSYKS NT
//
