ID A0A3B3H7A7_ORYLA Unreviewed; 576 AA.
AC A0A3B3H7A7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000027814.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000027814.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027814.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000027814.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027814.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3H7A7; -.
DR Ensembl; ENSORLT00000045376.1; ENSORLP00000027814.1; ENSORLG00000023898.1.
DR GeneTree; ENSGT01070000253760; -.
DR InParanoid; A0A3B3H7A7; -.
DR Proteomes; UP000001038; Chromosome 2.
DR Bgee; ENSORLG00000023898; Expressed in intestine and 10 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0035556; P:intracellular signal transduction; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR029495; NACHT-assoc.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR Pfam; PF14484; FISNA; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM01288; FISNA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 67..200
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
SQ SEQUENCE 576 AA; 66009 MW; FCFD3AAD3FEB6DF6 CRC64;
MTKAGNPTLL NEIYTELFIT EGGRGELNEE HELRQIEAAS RKADRAETSI RQEELFQLPA
GRQEPIRTVM TKGVAGIGKT VLTQKFTLDW AEGKNQDISA VVPLSFREMN LIRDEQHSLL
TLIQLFHPTL QKIPAEQLSV CKLLFIFDGL DKSRLSLDFN NCPLVSDVTH KSSVNVLLTN
LIQGRLLPSA LVWITSRPAA ANQIPPSCVD RLTEVRGFND AQKEEYFRRR FSDEELSSRI
ISHIKGSMSL YIMCEVPVFC WITAVVLENL LTTKKRKKLP TTLTDMYSHF LMEHQTSPQE
LTETDREVLL KLGRLAFEHL EKGNIMFYQE DLQQCGLDVT EASVYSGVCT EIFRRECEIF
QKAVYSFVHL SVQEFLAAVY MFHCYSKGKE KVIEDFLKNN MENTSLDEFL SRVMEKSLQS
QTGHLDLLVR FLHGLSVESN QKLLGGLLGQ RKKTPETIQR LLGCLLGHTE KDPETIQRAI
NNLKINSEGV SPDRSINIYH CLMEMKDLSV HQEIQEFLKS ENKSEKKLSE FHCSALAYTL
QMSEEVLYEL DLDQYKTSDE GKRRLIPAVR NCRKFR
//
