ID A0A3B3H7H2_ORYLA Unreviewed; 1223 AA.
AC A0A3B3H7H2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=EH domain binding protein 1 {ECO:0000313|Ensembl:ENSORLP00000027791.1};
GN Name=EHBP1 {ECO:0000313|Ensembl:ENSORLP00000027791.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000027791.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000027791.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027791.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000027791.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000027791.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3H7H2; -.
DR Ensembl; ENSORLT00000041424.1; ENSORLP00000027791.1; ENSORLG00000002562.2.
DR GeneTree; ENSGT00940000157597; -.
DR Proteomes; UP000001038; Chromosome 15.
DR Bgee; ENSORLG00000002562; Expressed in bone element and 15 other cell types or tissues.
DR CDD; cd21254; CH_EHBP1; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR022735; bMERB_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF43; EH DOMAIN-BINDING PROTEIN 1; 1.
DR Pfam; PF12130; bMERB_dom; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF10358; NT-C2; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM01203; DUF3585; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS51848; BMERB; 1.
DR PROSITE; PS51840; C2_NT; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 8..158
FT /note="C2 NT-type"
FT /evidence="ECO:0000259|PROSITE:PS51840"
FT DOMAIN 435..540
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 1043..1204
FT /note="BMERB"
FT /evidence="ECO:0000259|PROSITE:PS51848"
FT REGION 224..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 584..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..991
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1022..1047
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1190..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 179..223
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 251..271
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..287
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..762
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..826
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 944..972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..991
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1223 AA; 135821 MW; 2886E0F90B75E7F4 CRC64;
MASVWKRLQR VGKHASKFQF VASYQELMVE CTKKWQPDKL VVVWTRRSRR KSSKSHSWQP
GIKNPYRGVV VWPVPENIEI TVTLFKDPHA EEFEDKEWTF VIENESPSGR RKALATSSIN
MKQYASPMPT QTDVKLKFKP LSKKVVSATL QFSLSCIFLR EGKATDEDMQ SLASLMSMKQ
ADIGNLDDFE EENEEDEENR VNQEEKAAKI TELINKLNFL EDEDRESAPA MSSNPFDETD
DDLQTNHLNP FGDPDEEEPP AQQRPAEDSL HEHSSANPFN ELDEPETSSG NPFEEPDLDA
ELQPDPEPPK PKPRKGVRPV DMSKYLYADT SHTEEDELDE SNPFYEPKTS DPAGPAAAGP
SHNVDSSHKR MAPAPPSTTT GPSSSSTPVK PSCGPDKERT QPTRPSPVAA VMGRELASSS
PKLSPVPSPV LGGKPNASQS LLAWCREVTK NYRGVKITNF TTSWRNGLAF CALLHHFRPD
LIDYKSLGPQ DIKENNKKAY DGFASLGISR LLEPSDMVLL AIPDKLTVMT YLYQIRAHFS
GEELNVVQIE ANSSRSTYKV GDFETDTNAS VGQDKFYAEL NDVQHRQAEP QPTSPSTSTE
ANGADLEPQE GLSLTTGPLQ PSPTVPLQIS VPHTNATNSS NLTATVSEDR GVLLKAKTLD
LSEIRAEKEM EKETQQLEEA GQDGGEGDVE PAPSTRRGIS SSPPHQKLGF SYNRDADLIK
KKRASLRHSE SEPASEPRTS LVNHADGKQE PSPTSATSPA EKRVLSRQEE LKERARLLLE
QARRDAAIKA GSKNAPATTA RSSSVSDERD AERRKQLRER ARQLIAEARS GVKISDMSLL
DTARGSRGAP AGDVVDSGRS QDEDEEGGVL EEQVIFGGDG SVTAGSSAPA TALVTNPPPP
EALPAASSPP ELTNPAPELT SPGANSKNVD LKLKKMVEVG PRGVTSPTSP SSTSSSSSPS
ASSSSPSPLS PTEALEENAE ELRGERLRRA TERLRSPVVF NADSAVRKTQ LKSFSQYVEN
RPEVKRQKSV PEDLRRMEED RGSPAELEVH RQIEDEKAFK DTSQYVVGEL SALESEQRHI
DARAARVEKR LRYLMDTGNN KEEEEAMMQE WFMLVNKKNA LIRRQNQLSL LEKEHDLERR
FELLNRELRA MLAIEDWQKT EAQKRREQLL LDELVILVNK RDALVRDLDA QEKQAEEEDE
HLERTLEQNK GKMAKKEEKC VLQ
//
