ID A0A3B3H970_ORYLA Unreviewed; 1089 AA.
AC A0A3B3H970;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Myosin IF {ECO:0000313|Ensembl:ENSORLP00000028366.1};
GN Name=myo1f {ECO:0000313|Ensembl:ENSORLP00000028366.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000028366.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000028366.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000028366.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000028366.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000028366.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; A0A3B3H970; -.
DR STRING; 8090.ENSORLP00000028366; -.
DR Ensembl; ENSORLT00000042324.1; ENSORLP00000028366.1; ENSORLG00000009185.2.
DR GeneTree; ENSGT00940000158870; -.
DR InParanoid; A0A3B3H970; -.
DR OrthoDB; 1094820at2759; -.
DR Proteomes; UP000001038; Chromosome 4.
DR Bgee; ENSORLG00000009185; Expressed in mesonephros and 13 other cell types or tissues.
DR GO; GO:0015629; C:actin cytoskeleton; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005902; C:microvillus; IBA:GO_Central.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0031982; C:vesicle; IBA:GO_Central.
DR GO; GO:0051015; F:actin filament binding; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000146; F:microfilament motor activity; IBA:GO_Central.
DR GO; GO:0007015; P:actin filament organization; IBA:GO_Central.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR GO; GO:0030050; P:vesicle transport along actin filament; IBA:GO_Central.
DR CDD; cd01378; MYSc_Myo1; 1.
DR CDD; cd11827; SH3_MyoIe_If_like; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035507; Ie/If_SH3.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF663; UNCONVENTIONAL MYOSIN-IF; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 14..687
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 725..914
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT DOMAIN 1032..1089
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 564..586
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 912..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 957..971
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1000
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 107..114
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1089 AA; 124629 MW; B0EF1238D7BFBEA1 CRC64;
MAKYHWQSQN VKQSGVDDMV LLSKITEDAI VENLKKRYMD DYIFTYIGPV LISVNPFKQM
PYFTDREIEL YQGAAQYENP PHIYALTDNM YRNMMIDGEN QCVIISGESG AGKTVAAKYI
MGYISKVSGG GSKVQHVKDI ILQSNPLLEA FGNAKTVRNN NSSRFGKYFE IQFSRGGEPD
GGKISNFLLE KSRVVNQNEN ERNFHIYYQM IEGANAQQKE ALGVMTPDYY YYLNQSGTYK
VDGTNDSKDF QETLEAMQVI GIPADIQAQV LQIIAGILHL GNVSFIEAGN YGQVESTDLL
AFPAYLLGID PNRLQDKLTS RQMDSKWGGK SESINVTLNQ EQATYTRDAL AKALYARLFD
YLVEAINKAI QKPHEEFSIG VLDIYGFEIF KKNGFEQFCI NFVNEKLQQI FIELTLKAEQ
EEYVQEGIKW TPIDYFNNKI VCDLIENKLN PPGIMSVLDD VCATMHAKGE GADGTLLQKL
QAAVGTHEHF NSWNSGFVVH HYAGKVSYDI NGFCERNRDV LFPDLIELMQ SSEFDFIRSL
FPENLNTDKK GRPTTASSKI KKQANDLVNT LMKCTPHYIR CIKPNETKRP KDWEESRARH
QVEYLGLREN IRVRRAGFAY RRLFNKFLMR YAILTAETWP CWRGPEQQGV LHLLRSVNMD
NDQYQLGRTK VFVKNPESLF LLEEMRERKF DTFARIIQKA WRRFIARKKY EQMREEASDI
LYNSKERRKN SINRNFVGDY LGLEQRPELR QFLAKRERVD FADSVNKFDR RFKSIKRDLI
LTPKGIYLIG REKVKKGPEK GQIKEVLKRK MEFESISGVS LSTRQDDFFI LHETLYDSLL
ESNFKTEFLS LLSKRYEEVT KRKMTISFAD RLEFRVKKEG WGGGGSRVLV FQRGTGNVAQ
IKSAGKTLTI TIGDGLPKSS KPTRKSAVGS YGGGRNHVPS RAHQNGAARG HRAPAPQQSE
ITYSSPNKRG RPPNTALPKL GHQKTPRVPA NNQHDQGNLD FLSVPDQGMS GMQRKRSISH
RPPPAPKPQP RPQVPQCRAL YQYVGQDSDE ISFEVNDVIE LVREDPSGWW FGRIRGRQGM
FPGNYVEKI
//
