ID A0A3B3H9N3_ORYLA Unreviewed; 532 AA.
AC A0A3B3H9N3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Scavenger receptor class B member 1 {ECO:0000256|ARBA:ARBA00040821};
DE AltName: Full=SR-BI {ECO:0000256|ARBA:ARBA00042244};
GN Name=scarb1 {ECO:0000313|Ensembl:ENSORLP00000028225.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000028225.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000028225.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000028225.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000028225.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000028225.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane, caveola
CC {ECO:0000256|ARBA:ARBA00004189}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004189}.
CC -!- SIMILARITY: Belongs to the CD36 family.
CC {ECO:0000256|ARBA:ARBA00010532}.
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DR AlphaFoldDB; A0A3B3H9N3; -.
DR STRING; 8090.ENSORLP00000028225; -.
DR Ensembl; ENSORLT00000043751.1; ENSORLP00000028225.1; ENSORLG00000001304.2.
DR GeneTree; ENSGT00940000153372; -.
DR InParanoid; A0A3B3H9N3; -.
DR Proteomes; UP000001038; Chromosome 12.
DR Bgee; ENSORLG00000001304; Expressed in heart and 14 other cell types or tissues.
DR GO; GO:0005901; C:caveola; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008289; F:lipid binding; IBA:GO_Central.
DR GO; GO:0030169; F:low-density lipoprotein particle binding; IBA:GO_Central.
DR GO; GO:0005044; F:scavenger receptor activity; IBA:GO_Central.
DR GO; GO:0033344; P:cholesterol efflux; IBA:GO_Central.
DR GO; GO:0070508; P:cholesterol import; IBA:GO_Central.
DR GO; GO:0034381; P:plasma lipoprotein particle clearance; IBA:GO_Central.
DR GO; GO:0043654; P:recognition of apoptotic cell; IBA:GO_Central.
DR InterPro; IPR005428; CD36/SCARB1/SNMP1.
DR InterPro; IPR002159; CD36_fam.
DR PANTHER; PTHR11923:SF96; SCAVENGER RECEPTOR CLASS B MEMBER 1; 1.
DR PANTHER; PTHR11923; SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1; 1.
DR Pfam; PF01130; CD36; 1.
DR PRINTS; PR01610; CD36ANTIGEN.
DR PRINTS; PR01609; CD36FAMILY.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 442..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 532 AA; 60275 MW; EC13122984226FD6 CRC64;
MAIDKAKVAI GFVAAGAVTL TFGLISAFTG PAMMRYQVGK NTMIDPKNDM SYTMWKDLPV
PFFMSVYFFN VLNPEEVLKG EKPMVEQRGP YVYRKRCQKE NITFHPNYTV SYREYRTYYF
EPSMSVGNES DLVTVPNMLV LSAAVMMENL PYALRLLISA TFKTFKEGPF LTKTVGELMW
GYDSKLVDFL NQYLPGMLPS SGKFGLFAEF NNSNTGLFTI NTGKDDIRKV HRVDSWNGLT
QLSYWRTPQC NMINGTAGQM WPPFMTKEST LPFYSPDACR SLELVYQRTG EMLGIPLYRF
VAPRTMFANG SQYEPNQGFC PCRQSGLLNV SSCRHNSPVF ISHPHFFNAD PVLQDYVLGL
NPTEEEHGLF IDIHPLTGVP LNVSIRLQLN LYIKSVSGIT ETGKISEVVM PLLWFEESGY
IDGPVLNTFR TNLVVLPTVM EYMQYLLIAL GLVTVVVASV VHHKVKRSSN PVEVFSVTEN
PGVRKPARPD PNPNESIQIS NVLILIKKHF CRKKYDLLQN QGFLGPDWTR NF
//
