ID A0A3B3HAW7_ORYLA Unreviewed; 728 AA.
AC A0A3B3HAW7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ETS2 repressor factor {ECO:0000313|Ensembl:ENSORLP00000029064.1};
GN Name=ERF {ECO:0000313|Ensembl:ENSORLP00000029064.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000029064.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000029064.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029064.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000029064.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029064.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR Ensembl; ENSORLT00000032871.1; ENSORLP00000029064.1; ENSORLG00000023273.1.
DR Ensembl; ENSORLT00000045721.1; ENSORLP00000029360.1; ENSORLG00000023273.1.
DR GeneTree; ENSGT00940000157292; -.
DR OrthoDB; 4182934at2759; -.
DR Proteomes; UP000001038; Chromosome 16.
DR Bgee; ENSORLG00000023273; Expressed in pharyngeal gill and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF31; ETS DOMAIN-CONTAINING TRANSCRIPTION FACTOR ERF; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019};
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 27..107
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 146..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..409
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 438..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..531
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 728 AA; 79262 MW; 2C53265C0DA04270 CRC64;
MKTPGDTGFA FPDWAYKPES SPGSRQIQLW HFILELLRKE EYHDVIAWQG DYGEFVIKDP
DEVARLWGAR KCKPQMNYDK LSRALRYYYN KRILHKTKGK RFTYKFNFNK LVLVNYPFID
MGSSGSSVPQ SAPPVPTGAG THFRFPPSTP SEVLSPNEDL RSPGGMFSSV TRRMARGSVS
DCSDGTSVNS EIEEGNTGAA EERGERGVSG GGGGGPGGGG GYRSIIHPRL SHETLFRMYG
GPSNPAGHPG SRGPAGHRIH QEPLSPFPVS PLPGPGGASL LAPPLSPALS MTPTSHLPYT
PSPTLSPMLG SHFSFNPEDM KRYLQAHTQS VYNYGLSPRA FLQYPNIVIP HPHRPTPDKE
RGTAERAERA ATAGGERGGE RHHHPSLAHS AHHLPHHPHS AHPHPHSHPM HYPLHLGEEP
PHMSPFKFKL QPPPLGRKQR EGQSQNKPRQ SSLSSGSGSM SSTSGLGSSL SFGSDLSSAS
GSGVISASSS TQSLSSAGLP KIKVEPISDI ESEEEVEVTD ISDEDPDERD EDYEHFSLRH
SAASDHQQPN HRLANGTSAG QHQPHEEDLD EDVFKAPAPP PPALMPFFTS QHPHSSAQRG
LPAVKSEPAE PGESNTSPSQ TAATGAAQTK CIPLKLRFKR RWSEDQRMET SQEESDDKKV
RPEEERERGR QSNGCMEMEE DGTGRGEGDS PPPLAYEGSL GTPLASHQRV SAELHRATAQ
LSLENKDC
//
