ID A0A3B3HCI7_ORYLA Unreviewed; 675 AA.
AC A0A3B3HCI7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Histone deacetylase 10 {ECO:0000313|Ensembl:ENSORLP00000029547.1};
GN Name=hdac10 {ECO:0000313|Ensembl:ENSORLP00000029547.1};
OS Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=8090 {ECO:0000313|Ensembl:ENSORLP00000029547.1, ECO:0000313|Proteomes:UP000001038};
RN [1] {ECO:0000313|Ensembl:ENSORLP00000029547.1, ECO:0000313|Proteomes:UP000001038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029547.1,
RC ECO:0000313|Proteomes:UP000001038};
RX PubMed=17554307; DOI=10.1038/nature05846;
RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., Yamada T.,
RA Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., Shimada A.,
RA Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., Asakawa S.,
RA Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., Sugano S.,
RA Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., Nomoto H., Nogata K.,
RA Morishita T., Endo T., Shin-I T., Takeda H., Morishita S., Kohara Y.;
RT "The medaka draft genome and insights into vertebrate genome evolution.";
RL Nature 447:714-719(2007).
RN [2] {ECO:0000313|Ensembl:ENSORLP00000029547.1}
RP IDENTIFICATION.
RC STRAIN=Hd-rR {ECO:0000313|Ensembl:ENSORLP00000029547.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; A0A3B3HCI7; -.
DR Ensembl; ENSORLT00000047044.1; ENSORLP00000029547.1; ENSORLG00000009350.2.
DR GeneTree; ENSGT00940000160061; -.
DR Proteomes; UP000001038; Chromosome 13.
DR Bgee; ENSORLG00000009350; Expressed in animal zygote and 14 other cell types or tissues.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR PANTHER; PTHR10625:SF18; POLYAMINE DEACETYLASE HDAC10; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001038}.
FT DOMAIN 26..321
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 379..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 675 AA; 74275 MW; 1E978458E470BCAE CRC64;
MGTALIYDEE MTKYKLLWVD PACKIEVPER LTVSHGALVR NGLTDRCICL PVREAVDAEI
LLVHSEEYLE AVKQTPHMTL EDLKEFTLQY GDVYFHPNIY HCAKLAVGSA LQLVDSVLMG
KVKNGMALVR PPGHHSMRSA ANGFCVFNNV AIAAQYAKQK YGVKRILIVD WDIHHGQGVQ
YCFEDDPSVL YFSWHRYEHQ KFWPNLKDSD YDIVGKGEGA GFNINVPWNK VGMENSDYLS
VFCHVLLPIA YEFCPDLVLV CAGFDSAIGD LEGEMCATPD IFAHLTYLLM NLAEGKLCAV
LEGGYNLTSL AQSVCQTVQT LLGDPLPPLT NLTGPCRSTL ESLQCVRAAH RQHWSCLRHA
VDLPTFEIST IRIKSSGEEN KDEAEVWEEQ KSPEEKIWPE PPKRVSPRVC SAVVLPDGVV
CPDACERLSS SEDLGPHLLT LKKDFLKDAD DSAVTALSRV FSLIDKMKNN EIRNGLALVG
DAAMTMTCVV QHVAAEVDSR VFLVCVGNGN IPGHIIEDGK TLVVQISGED TEEQGSKYYV
PVCLKKGCTD TSGFAQAMFS LLLPLGYQHN PSLVLLVRMP GSGVCDIMWQ QLTALLQSFA
QGHTLVLLQE DDKACVGPTA SILLGNPAPP LGQLPASLKE DAEAVERLRS RLQADWNLLL
ATGESTKEST LMSGT
//
